What you are asking for is client side image sampling for image
displayed in a browser.  It's not a maps question, so you might find
something if you search in more general terms ... but I think the
answer is "no".

If the images are being "created" e.g. drawing a line of a certain
colour then you could access the data used to do the creating (such
as  parsing it out of KML)

If you want some kind of interactivity with a bar chart image or
whatever that you are creating server-side, you might use traditional
HTML methods and also create an image map server-side that the client
can use to select areas.

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