Dear Jason,
I hate to bug you but we wanted to get your quick check on something as the GPC 
sites are doing their CDM work in support of your study.

Apologies for not being as close to your study but wanted to confirm something 
about how the CDM is being loaded and potential implications for your study as 
it's the first big thing using medications from the CDM.

The CDM 
http://pcornet.org/wp-content/uploads/2014/07/2015-07-29-PCORnet-Common-Data-Model-v3dot0-RELEASE.pdf
on page 13 specifies that the prescribing tables and the dispensing tables 
should not contain

-          inpatient medication administrations

-          active medication lists resulting from medication reconciliation

Prescribing should obviously have outpatient prescriptions but it's unclear to 
some regarding physician inpatient orders.  The table specification in written 
largely in language of outpatient prescriptions but the page 13 figure 
indicates that prescribing encompasses physician orders that spawn both 
dispenses and administrations.

I would just be concerned that if sites are conservative in only loading 
ambulatory meds, we're going to have limited CDM data to support studies that 
want to include inpatient and emergency room medication exposures.

As you look at your early sites, what are you seeing?

Does that match what exposures you wish you had?

Bottom line: are you only looking at outpatient prescribing or dispensing 
exposure to antibiotics or does your study need inpatient and emergency room 
medication exposure?

My personal bias is to exclude the admins and the med rec at this point but 
include both inpatient and outpatient medication orders written by the 
physician.

Russ Waitman, PhD
Director of Medical Informatics
Associate Vice Chancellor for Enterprise Analytics
Professor, Department of Internal Medicine
University of Kansas Medical Center, Kansas City, Kansas
913-945-7087 (office)
[email protected]<mailto:[email protected]>
http://www.kumc.edu/ea-mi/
http://informatics.kumc.edu<http://informatics.kumc.edu/>
http://informatics.gpcnetwork.org<http://informatics.gpcnetwork.org/> - a 
PCORnet collaborative

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