On Fri, 2006-05-05 at 16:46, Kevin Toppenberg wrote:
> See below
> 
> On 5/5/06, Ruben Safir <[EMAIL PROTECTED]> wrote:
> > I was reading this today:
> >
> > While these numbers are impressive, ....
> 
> What numbers?  Did you mean to include a link to an article?
> 
> they are likely to be a significant
> > underestimation of the problem.  First, the two studies from which the
> > statistics are extracted are believed to offer conservative figures
> > because they were limited to injuries of a specified level of harm, they
> > required a high threshold to determine whether an adverse event was
> > preventable or negligent, and they included only those errors documented
> > in patient records.2 Second, these statistics represent errors in
> > hospitals only. More recently, Barker and colleagues observed a
> > persistence of the problem in defining 19% of doses administered in
> > health care facilities to be in error and 7% rated as potentially
> > harmful.3
> >
> > 20% of the doses is impressive.
> 
> Reuben, I am always very skeptical of these studies.  Does 20% of all
> doses make any sense to you? 

Yes - not only does it make sense, but I've confirmed this rate in my
own studies both in ***ambutitary*** care settings (ir:  at the counter
in Rite-Aid) and in the hospital (following the nurses around).  And
this is while I was watching them.  In fact, my data showed nearly 27%
of the doses to be medically incorrect, and nearly 47% of the IV drugs
given on the floors as being incorrect, and that was just from what I
could see and not accounting for dosing errors, or miss use of drugs by
physicians which my students and I did not catch even before following
the nurse around.

 
>  I have a hard time believing it.  A
> typical patient may well be on 8 drugs in the hospital, and TID --> 24
> doses a day.  So 20%=5 erroneous does a day?  I bet this is a
> statistacal aberration.  Or else I am very nieve.  Perhaps the bigger
> the numbers quoted, the more likely that one will get one's paper
> published?
> 
> Who was working with he Pharmacy
> > modules?  Was that Kevin?  Is there a means for error reporting and
> > tracking?
> 
> I haven't seen anything about error tracking, but I am very focused on
> a small part of the pharmacy package right now ... drug
> classifications with the VA classes.  What a headache!  

At one point it was discussed about what to do with Physician Order
Entry and interaction warnings.  I strongly recommend the inclusion of
those warnings. In addition, if it was me, nobody would ever order a med
without the prescribing information on the screen write next to the drug
and annotation from the department heads and the pharmacy.


> I thought I
> was done, and then found 5,000 more drugs in the FDA database that
> were completely new to the VA database, so there are no potential
> matches that can be used to suggest drug classes for the new drugs. 
> Also, I have never seen so many drugs that I have never heard of in my
> life.  All kinds of combination tablets with unfamiliar tradenames....
> 

Not a surprise.  My gut tells me that the FDA listing is not the best
place to work off of.

Ruben



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