Hi
You can easily create the nodif_brain image yourself with the FSL tools. For 
example:

fslroi data nodif 0 1   (assuming the first volume is a b=0, which it is in the 
HCP data)
fslmaths nodif -mas nodif_brain_mask nodif_brain

However, note that the HCP diffusion data are resampled in T1w space as part of 
the preprocessing. So if your seed ROIs are in that space you don’t need to 
provide any transformation to probtrackx. Also, if your seed ROIs are in MNI 
space, then you can use the transformations provided by the HCP, which are in 
<subject>/MNINonLinear/xfms

Cheers
Saad

On 1 Jul 2014, at 08:36, Linden Parkes 
<[email protected]<mailto:[email protected]>> wrote:

Hi,

I'm trying to use FSL FDT to do some probabilistic tractography. I have run 
bedpostx and am now trying to run registration within FDT.
According to an error I'm getting from the FSL FDT gui, I'm meant to have a 
nodif_brain image in the bedpostx directory but this is not the case. I do have 
the nodif_brain_mask image however.

Am I missing something? Is this nodif_brain image meant to come with HCP 
datasets (e.g the new S500 release) or am I meant to create it myself? I can't 
see any mention of it in the S500 release reference manual.

Or perhaps I shouldn't be using it at all? I figured I needed to use it in 
order to set the seed space to diffusion space. But if I'm wrong on this could 
someone tell me which file to use for the "seed to diff transform" and "diff to 
seed transform" in PROBTRACKX?

Cheers,
Linden

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--
Saad Jbabdi
University of Oxford, FMRIB Centre

JR Hospital, Headington, OX3 9DU, UK
(+44)1865-222466  (fax 717)
www.ndcn.ox.ac.uk/team/researchers/saad-jbabdi<http://www.ndcn.ox.ac.uk/team/researchers/saad-jbabdi>


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