Hey - Thanks for the crash course on CIFTI. That cleared a few things up
for me, but I'm still not sure how to perform the tractography.

Cheers,
Linden


On 9 July 2014 07:14, Timothy Coalson <[email protected]> wrote:

> The extension for CIFTI files is .[type].nii, where type is dconn,
> dtseries, dscalar, dlabel, pconn, or another such specifier.  It ends in
> .nii because CIFTI uses the NIFTI-2 format, which specifies that the
> extension must be .nii, but includes a specialized XML header extension
> instead of using the NIFTI header for spacing info, etc.  Also, we usually
> gzip our volume files (CIFTI must not be gzipped when used, as we need
> on-disk random access due to large file sizes), so volume files we
> distribute will generally end in .nii.gz.
>
> The standard extensions are listed in the specification, see Appendix A in
> http://www.nitrc.org/forum/attachment.php?attachid=342&group_id=454&forum_id=1955
> for the list, but refer to the main specification in
> http://www.nitrc.org/forum/forum.php?thread_id=4380&forum_id=1955 for how
> "unknown" works (it still must end in .nii).
>
> Tim
>
>
>
> On Mon, Jul 7, 2014 at 11:17 PM, Linden Parkes <[email protected]>
> wrote:
>
>> Ah okay, what is the file extension for CIFTI? I can only see .nii and
>> .gii files.
>>
>> I tried following those instructions but came unstuck at the “FreeSurfer
>> Registration” step because I could not find the struct.nii.gz file in the
>> HCP datasets.
>>
>> I’d like to perform striatal segmentation with tractography.
>> Specifically, using subcortical regions such as the accumbens, caudate and
>> putamen. To this end, I figured that using the aparc cortical regions as
>> “Classification targets”  and choosing Matrix2 was most appropriate. One
>> method I thought of trying was just to get binary volume masks for all the
>> cortical regions in aparc and submitting them. But from my reading of the
>> FSL mailing list, it appears that using surfaces as opposed to volumes is
>> preferable. However, as mentioned above, I came unstuck following the FSL
>> user guide.
>>
>> Hope this makes sense
>>
>> Cheers,
>> Linden
>>
>> ——————————————————————
>>
>> *Linden Parkes*
>>
>> *PhD Candidate*
>> *Monash Clinical & Imaging Neuroscience (MCIN)*
>> *School of Psychological Sciences*
>> *Monash Biomedical Imaging*
>> *Monash University*
>>
>> *A: 770 Blackburn Rd, Clayton, 3168, **Vic, Australia*
>> *T: +61 3 9902 9435 <%2B61%203%209902%209435>  |  0402 516 574*
>> *E: [email protected] <[email protected]>*
>> *W: www.med.monash.edu.au/psych/mcin/
>> <http://www.med.monash.edu.au/psych/mcin/>*
>>
>>
>> From: Glasser, Matthew [email protected]
>> Reply: Glasser, Matthew [email protected]
>> Date: 8 July 2014 at 2:05:55 pm
>> To: Linden Parkes [email protected]
>>
>> Cc: [email protected] [email protected]
>> Subject:  Re: [HCP-Users] Probtrackx surface analysis
>>
>>  HCP data is NIFTI/GIFTI/CIFTI, so the particular files you have there
>> are NIFTI volumes.  The GIFTI surface aparc data are in
>>
>>
>> ${StudyFolder}/${Subject}/MNINonLinear/fsaverage_LR32k/100307.${Hemisphere}.aparc.32k_fs_LR.label.gii
>>
>>
>> To use them with probtrackx2, you’ll need to follow the instructions here
>> (unfortunately probtrackx2 currently doesn’t support standard GIFTI
>> surfaces and label files):
>>
>>  http://fsl.fmrib.ox.ac.uk/fsl/fslwiki/FDT/UserGuide#Using_surfaces
>>
>> To know what matrix you should use, I’d need to know a little bit more
>> about the question you are asking.  matrix2 with nodif_brain_mask as the
>> tract space mask will produce an enormous file.
>>
>> Peace,
>>
>> Matt.
>>
>>  From: Linden Parkes <[email protected]>
>> Date: Monday, July 7, 2014 at 5:21 PM
>> To: Matt Glasser <[email protected]>
>> Cc: "[email protected]" <[email protected]>
>> Subject: Re: [HCP-Users] Probtrackx surface analysis
>>
>>  Oh, I thought the HCP data was distributed in cifti and gifti?
>> As a first pass I wanted to use all surfaces in aparc as classification
>> targets for a few subcortical volumes rois and am a bit unsure on how to do
>> that.
>> I'd like to pull out matrix2 for this (seems most appropriate). Can I
>> submit the nodif_brain_mask as the "tract space mask" for this?
>>
>> Cheers
>> Linden
>> On 08/07/2014 2:08 am, "Glasser, Matthew" <[email protected]>
>> wrote:
>>
>>>  You would use the white matter surfaces in
>>> ${StudyFolder}/${Subject}/T1w/fsaverage_LR32k.  The distributed diffusion
>>> data are already in T1w space, so you don’t need to provide transformation
>>> matrices.  The surface reference image can be any of the files in 
>>> ${StudyFolder}/${Subject}/T1w
>>> or ${StudyFolder}/${Subject}/T1w/Diffusion.
>>>
>>> Neither of the files you mention are CIFTI files.  What cortical
>>> regions are you wanting to track from?
>>>
>>> Peace,
>>>
>>> Matt.
>>>
>>>  From: Linden Parkes <[email protected]>
>>> Date: Monday, July 7, 2014 at 3:49 AM
>>> To: "[email protected]" <[email protected]>
>>> Subject: [HCP-Users] Probtrackx surface analysis
>>>
>>>   Hi HCP users,
>>>
>>>  I’m trying to run probtrackX on some HCP data, can someone provide some
>>> guidance on how to run this using surfaces? I’m following the FSL user
>>> guide but they often refer to files which are absent from the HCP data as
>>> far I can tell. (e.g., "and also that you have a file called
>>> struct.nii.gz that you have used as an input to FreeSurfer
>>> <http://fsl.fmrib.ox.ac.uk/fsl/fslwiki/FreeSurfer> recon_all program."
>>>
>>>  Basically, I’d like to define subcortical seeds and track to cortical
>>> surfaces.
>>>
>>>  For the subcortical seed regions I can easily create binary masks to
>>> use as seeds using fslmaths based on intensity values from the freesurfer
>>> LUTs. I could do the same with the cortical regions but I have read that
>>> tracking to cortical regions is best done with surfaces instead of volumes.
>>>
>>>  So, when selecting “classification targets” can I simply add in a cifti
>>> file? (e.g., 100307/T1w/aparc+aseg.nii.gz OR
>>> 100307/T1w/aparc.a2009s+aseg.nii.gz)** and then tell probtrackX to output
>>> the matrices I want?
>>>
>>>  **I assume using the files in the T1w dir is best because these are in
>>> the same space as the diffusion data and therefore don’t require
>>> transformation.
>>>
>>>  On a different note, if I select a surface file as a seed instead, it
>>> asks for a “surface reference image” for Freesurfer. Which file is best
>>> used for this purpose?
>>>
>>>  Cheers,
>>> Linden
>>>
>>> ——————————————————————
>>>
>>>  *Linden Parkes*
>>>
>>>  *PhD Candidate*
>>> *Monash Clinical & Imaging Neuroscience (MCIN)*
>>> *School of Psychological Sciences*
>>> *Monash Biomedical Imaging*
>>> *Monash University*
>>>
>>>  *A: 770 Blackburn Rd, Clayton, 3168, **Vic, Australia*
>>> *T: +61 3 9902 9435 <%2B61%203%209902%209435>  |  0402 516 574*
>>> *E: [email protected] <[email protected]>*
>>> *W: www.med.monash.edu.au/psych/mcin/
>>> <http://www.med.monash.edu.au/psych/mcin/>*
>>>
>>>  B7AE8BF0-4F0C-4F0B-9BDE-B582B9331FA1
>>>
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