Hi Eric

Not really, but it depends on how many do you mean by "many maximas”? Also what 
type of ODF reconstruction and regularisation you perform? Have you tried your 
code to non-HCP data or just phantoms? Most of the times numerically-simulated 
phantoms represent a best-case scenario.

You are right, motion correction and eddy current correction has already been 
performed in the data.

Cheers
Stam
 

 
On 10 Jul 2014, at 20:40, Eric Lum <[email protected]> wrote:

> Hello sir/madam,
> 
> I am using a HCP preprocessed dMRI dataset to calculate fiber ODFs.  
> Since my code works with single shell data only, I took the data in  
> the b = 2000 s/mm^2 range (which in my understanding is okay since  
> gradients in each shell are uniformly distributed).
> 
> The calculated ODFs are showing the fiber trends fairly well. However  
> the ODFs are exhibiting many maximas which to me seems like the brain  
> images are slightly mis-aligned. Looking through the manual, it seems  
> registration has already been performed to mitigate motion artifacts  
> and eddy current effects in these datasets. (I don't think it's a  
> problem with the code as ODF construction using phantoms didn't have  
> this effect, but it's possible).
> 
> I'm wondering if anyone's encountered this problem? Any help would be  
> much appreciated.
> 
> Thanks for your time,
>   Eric
> 
> 
> 
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