Hi Joelle,
Here are the HCP Inclusion Criteria:
Inclusion Criteria:
No significant history of psychiatric disorder, substance abuse, neurological,
or cardiovascular disease
-No person report of diagnosis by a treating physician
-No hospitalization
No pharmacologic or behavioral treatment (12 months duration or longer) by a
specialty-trained physician (psychiatrist, neurologist, cardiologist) or
therapist (e.g., psychologist, social worker)
-Childhood ADHD with no current treatment is allowed
-Transient childhood seizures allowed (clarify what type)
-Migraines allowed if not taking daily psychoactive medications
Age 22 to 35
Ability to give valid informed consent
MMSE score of 24 or above
Here are the HCP Exclusion Criteria:
Two or more non-provoked (e.g., not due to fever) seizures or a diagnosis of
epilepsy
Any genetic disorder, such as Cystic Fibrosis
Use of daily prescription medications for migraines in the past month
Multiple Sclerosis, Cerebral Palsy
Brain tumor or Stroke
Currently on chemotherapy or immunomodulatory agents, or history of radiation
or chemotherapy that could affect the brain
Sickle Cell Disease
Thyroid Hormone Treatment in the past month
Treatment for Diabetes in the past month (do not exclude for gestational or
diet controlled diabetes)
Head Injury If:
LOC>30 minutes or Amnesia >24 hours
Change in Mental Status >24 hours or CT findings consistent with TBI
3 or more concussive (mild) TBIs
Premature Birth (Born >37 weeks for non-twins, born <34 weeks for twins. If
weeks unknown, less than 5 lbs. at birth for non-twins.
Current Pregnancy
Unsafe metal or devices in the body (Cardiac Pacemaker, cochlear implant,
aneurism clip)
Moderate to Severe Claustrophobia
Hope that helps.
Best,
Jenn
Jennifer Elam, Ph.D.
Outreach Coordinator, Human Connectome Project
Washington University School of Medicine
Department of Anatomy and Neurobiology, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
[email protected]
www.humanconnectome.org
From: Joelle Zimmermann [mailto:[email protected]]
Sent: Monday, November 30, 2015 11:12 AM
To: Jennifer Elam
Cc: [email protected]
Subject: Re: [HCP-Users] Demographic and behavioral subject data
Hi Michael and Jennifer,
Thank you both for your help, much appreciated. One remaining question - is
there currently any cutoff for cognitive scores (i.e. for the MMSE for ex) for
subjects being included in the 500 release dataset? Can't find mention of it
in the ref manual, so Im guessing probably not.
Thanks,
Joelle
On Mon, Nov 30, 2015 at 11:49 AM, Jennifer Elam <[email protected]> wrote:
Hi Joelle,
All the HCP subjects are considered healthy young adults with no diagnosed
cognitive abnormalities. They do, of course, have a range of abilities and
scores on the behavioral tests we conduct.
There is a lot of information in Chapter 1 of the current 500 Subjects
Reference Manual
<http://humanconnectome.org/documentation/S500/HCP_S500+MEG2_Release_Reference_Manual.pdf>
for navigating the behavioral data and for filtering subjects—please check it
out. There is also a “Download CSV button” at the upper right of the subject
Dashboard that will allow you to download all the open access behavioral data
in one spreadsheet. Look at the sections of the Reference Manual on Restricted
access data to see if you need to apply for access to that data for your
purposes.
As detailed in the Introduction section of the Reference Manual, subjects that
were originally acquired or released in different quarters/releases can be
combined in analyses because we ran all subjects through the same analysis
pipelines as of the 500 subjects release (as long as you are using data
currently in ConnectomeDB, the S500 Connectome in a Box, or S500 S3 Bucket
data). Again, as stated in the Ref Manual Introduction, one thing you should
be aware of is that the fMRI data collected in Q1 and part of Q2 was
reconstructed with a slightly different reconstruction algorithm than
subsequent data. You can filter on Study Completion>Image Reconstruction Info:
3T MR>3T MR fMRI Recon Version, if you think it might make a difference to your
analyses.
In the upcoming 900 Subjects release (coming within the next couple of weeks!),
the new subject data will also be comparable to the 500 Subject release data.
Pipeline changes since the S500 release have been mostly minor and have only
added to the data available (more details to come).
Best,
Jenn
Jennifer Elam, Ph.D.
Outreach Coordinator, Human Connectome Project
Washington University School of Medicine
Department of Anatomy and Neurobiology, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
[email protected]
www.humanconnectome.org
From: [email protected]
[mailto:[email protected]] On Behalf Of Joelle Zimmermann
Sent: Monday, November 30, 2015 10:27 AM
To: [email protected]
Subject: [HCP-Users] Demographic and behavioral subject data
Hello everyone,
I want to pick a group of subjects from the 500 subjects +MEG2 for which I
will perform (rsfMRI and dMRI) analysis. These should be young, healthy,
subjects that have no abnormalities and cognitively able.
Does anyone have any pointers about how I can go weeding out subjects? Under
"Subject Information" of all subjects, I can see a list of all subjects, where
I can see age, release and gender. And when I click on the subject, I find a
bunch of behavioral tests and their results for that subject.
Should subjects from different releases be combined? Which is the most recent
release?
Are there certain scores for cognitive assessments that are considered to weed
out the cognitively able, healthy subjects? Is this data available somewhere in
a spreadsheet form, without having to go into each subject and scrolling though
their various assessment scores?
Anything would help.
Thanks,
Joelle
_______________________________________________
HCP-Users mailing list
[email protected]
http://lists.humanconnectome.org/mailman/listinfo/hcp-users
_______________________________________________
HCP-Users mailing list
[email protected]
http://lists.humanconnectome.org/mailman/listinfo/hcp-users
