Hi everyone,

I'm interested in using the FIX-denoised data, and am currently looking at
the extended package, as I'm interested in the volumetric data.

I'm wondering whether the motion parameters have already been regressed out
from the FIX denoised rfMRI_REST1_LR_hp2000_clean.nii.gz?

I'm assuming yes, that the FIX denoised actually already deals with this by
separating the motion-related noise into a component and filtering that out
of the signal?  I assume so based on the following snippet from the manual
describing FIX-ed data:
"As part of this cleanup, we also used 24 confound timeseries derived from
the motion estimation (the 6 rigid-body parameter timeseries, their
backwards-looking temporal derivatives, plus all 12 resulting regressors
squared — Satterthwaite et al., 2013). The motion parameters have the
temporal highpass filtering applied to them and are then regressed out of
the data aggressively, as they are not expected to contain variance of
interest."
Am I correct?

Has white matter and/or cerebrospinal fluid been regressed already from the
FIX denoised fMRI timeseries?

Has physiological data (“rfMRI_REST1_LR_Physio_log”) already been regressed
from the FIX denoised data?

Any pointers would be much appreciated.

Thanks,
Joelle

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