Hi Michael,

Thanks for your help. I have a few more questions below..

Has an average timeseries for WM (and CSF) signal been already computed by
HCP?
Perhaps this is the "rfMRI_REST1_LR_WM.txt" and the
"rfMRI_REST1_LR_CSF.txt" in the FIX extended package?

Is there a recommended way of regressing these out?

Related to my previous question: Has physiological data
(“rfMRI_REST1_LR_Physio_log”) already been regressed from the FIX denoised
data?
I cannot actually find a rfMRI Physio log file in the FIX-ed dataset, I can
only find this Physio log file in the minimally preprocessed dataset. I
suppose I can use that one? But I'd assume there should be one in the
FIX-ed dataset folder as well...

Thanks,
Joelle

On Wed, Dec 9, 2015 at 2:43 PM, Harms, Michael <[email protected]> wrote:

>
> Hi,
> See inline below.
>
> --
> Michael Harms, Ph.D.
> -----------------------------------------------------------
> Conte Center for the Neuroscience of Mental Disorders
> Washington University School of Medicine
> Department of Psychiatry, Box 8134
> 660 South Euclid Ave. Tel: 314-747-6173
> St. Louis, MO  63110 Email: [email protected]
>
> From: Joelle Zimmermann <[email protected]>
> Date: Wednesday, December 9, 2015 1:26 PM
> To: "[email protected]" <[email protected]>
> Subject: [HCP-Users] FIX-denoised
>
> Hi everyone,
>
> I'm interested in using the FIX-denoised data, and am currently looking at
> the extended package, as I'm interested in the volumetric data.
>
> I'm wondering whether the motion parameters have already been regressed
> out from the FIX denoised rfMRI_REST1_LR_hp2000_clean.nii.gz?
> YES
>
> I'm assuming yes, that the FIX denoised actually already deals with this
> by separating the motion-related noise into a component and filtering that
> out of the signal?  I assume so based on the following snippet from the
> manual describing FIX-ed data:
> "As part of this cleanup, we also used 24 confound timeseries derived from
> the motion estimation (the 6 rigid-body parameter timeseries, their
> backwards-looking temporal derivatives, plus all 12 resulting regressors
> squared — Satterthwaite et al., 2013). The motion parameters have the
> temporal highpass filtering applied to them and are then regressed out of
> the data aggressively, as they are not expected to contain variance of
> interest."
> Am I correct?
> YES
>
> Has white matter and/or cerebrospinal fluid been regressed already from
> the FIX denoised fMRI timeseries?
> NO
>
> Has physiological data (“rfMRI_REST1_LR_Physio_log”) already been
> regressed from the FIX denoised data?
> NO
>
> Any pointers would be much appreciated.
>
> Thanks,
> Joelle
>
>
>
>
>
>
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