Hello HCP users, I'm planning on doing some funcional connectivity analysis to perform a parcellation with a method similar to the one presented in Cohen 2008 (1).
Although my intention is to use the ICA-FIX denoised data, I'm confused about the convenience of making some extra processing resgressing the mean gray timecourse. I know that HCP team usually doesn't recommend to do that, but reading the Smith 2013 (2) paper and the results presented in one poster from the last OHBM by them, it seems that I should. Smith says: "Preliminary analyses of measures of motion-related artefacts indicate that the ICA-FIX process greatly reduces but does not, in some datasets, totally eliminate motion artefacts that are frame- specific and non-spatially-specific." and also "... some analyses, such as gradient-based investigation of functional boundaries (Cohen et al., 2008),may benefit from MGT regression, as it may help highlight transitions in connectivity patterns across the cortex" The OHBM poster is this: https://ww4.aievolution.com/hbm1501/index.cfm?do=abs.viewAbs&abs=3394, and the results show that "FIX and MGTR appear to improve relationships of individual differences with resting state functional connectivity " Taking this into account, do you still recommend not to perform MGTR? Otherwise, can you offer some guidelines to perform this regression? Thank you very much in advance! (1) Cohen, A. L., Fair, D. A., Dosenbach, N. U. F., Miezin, F. M., Dierker, D., Van Essen, D. C., … Petersen, S. E. (2008). Defining functional areas in individual human brains using resting functional connectivity MRI. NeuroImage, 41(1), 45–57. http://doi.org/10.1016/j.neuroimage.2008.01.066 (2) Smith, S. M., Beckmann, C. F., Andersson, J., Auerbach, E. J., Bijsterbosch, J., Douaud, G., … Glasser, M. F. (2013). Resting-state fMRI in the Human Connectome Project. NeuroImage, 80, 144–168. http://doi.org/10.1016/j.neuroimage.2013.05.039 Raquel Viejo Sobera, PhD Cognitive NeuroLab Hospital de la Santa Creu i Sant Pau www.cognitiveneurolab.org ____________________________________ Universitat Oberta de Catalunya Faculty of Health Sicences Avinguda Tibidabo 39-43, 08035 Barcelona 93 450 (5370) | [email protected] [image: Universitat Oberta de Catalunya] Este mensaje se dirige exclusivamente a quien se destina y puede contener información privilegiada o confidencial y datos de carácter personal, cuya difusión está regulada por la Ley orgánica de protección de datos y la Ley de servicios de la sociedad de la información. Si usted no es la persona destinataria indicada (o la responsable de la entrega a quien se destina), no debe copiar este mensaje ni entregarlo a terceros bajo ningún concepto. Si ha recibido este mensaje por error o lo ha conseguido por otros medios, le rogamos que nos lo comunique inmediatamente por esta misma vía y proceda a su eliminación irreversible. Antes de imprimir este mensaje electrónico piense en el medio ambiente. _______________________________________________ HCP-Users mailing list [email protected] http://lists.humanconnectome.org/mailman/listinfo/hcp-users
