Dear Sir,

We are using VERIO MRI scanner with spatial resolution about 2mm and we had
only 32 Diffusion directions. That’s definitely  a difference to the HCP
data set. Any suggestions how to resolve this issue would be greatly
appreciated.


Thanks
Vasudev

On 21 June 2016 at 21:36, Dev vasu <[email protected]>
wrote:

> Dear Sir,
>
> The vestibulopathy subject scans are from scanner outside HCP, we here in
> LMU Munich use Siemens Skyra 3T scanner, in such case how to neutralize or
> eliminate the differences which may occur due to scanner differences ?.
>
>
> Thanks
> Vasudev
>
>
> On 21 June 2016 at 21:29, Harms, Michael <[email protected]> wrote:
>
>>
>> Hi,
>> I would use a measure that relates in a concrete way to the underlying
>> neuroanatomy, such as cortical thickness.
>>
>> There may be a bigger issue here, which is that I’m now guessing that
>> your vestibulopathy subjects are coming from scans collected from outside
>> HCP?  If so, you have a major confound, because you will be attempting to
>> compare two groups that were collected on completely different scanners.
>> In which case, any difference you find could be attributed to just scanner
>> difference effects.
>>
>> cheers,
>> -MH
>>
>> --
>> Michael Harms, Ph.D.
>> -----------------------------------------------------------
>> Conte Center for the Neuroscience of Mental Disorders
>> Washington University School of Medicine
>> Department of Psychiatry, Box 8134
>> 660 South Euclid Ave. Tel: 314-747-6173
>> St. Louis, MO  63110 Email: [email protected]
>>
>> From: <[email protected]> on behalf of Dev vasu <
>> [email protected]>
>> Date: Tuesday, June 21, 2016 at 2:02 PM
>> To: "Harms, Michael" <[email protected]>
>> Cc: "[email protected]" <[email protected]>
>> Subject: Re: [HCP-Users] Spatial normalization of 50 Subjects T1w images
>>
>> Dear Professor,
>>
>> I was advised to do VBM, I understand questions pertaining to biological
>> validity of VBM and interpretation issues. I would like to investigate the
>> cortical regional differences between health controls and controls with
>> vestibulopathy , If you have any other suggestion pertaining to this task i
>> would really appreciate your response.
>>
>>
>>
>> Thanks
>> Vasudev
>>
>> On 21 June 2016 at 20:47, Harms, Michael <[email protected]> wrote:
>>
>>> Hi,
>>> If I may, why VBM?  VBM is prone to a number of interpretational issues,
>>> as opposed to say cortical thickness, which is already available for you as
>>> part of the HCP processing.
>>>
>>> cheers,
>>> -MH
>>>
>>> --
>>> Michael Harms, Ph.D.
>>> -----------------------------------------------------------
>>> Conte Center for the Neuroscience of Mental Disorders
>>> Washington University School of Medicine
>>> Department of Psychiatry, Box 8134
>>> 660 South Euclid Ave. Tel: 314-747-6173
>>> St. Louis, MO  63110 Email: [email protected]
>>>
>>> From: <[email protected]> on behalf of Dev vasu <
>>> [email protected]>
>>> Date: Tuesday, June 21, 2016 at 1:30 PM
>>> To: Stamatios Sotiropoulos <[email protected]>, "
>>> [email protected]" <[email protected]>,
>>> "Glasser, Matthew" <[email protected]>, Timothy Brown <
>>> [email protected]>
>>> Subject: [HCP-Users] Spatial normalization of 50 Subjects T1w images
>>>
>>> Dear Sir ,
>>>
>>>
>>> I am using HCP data ( 50 subjects ) + 50 patients with bilateral
>>> vestibular paresis to examine the Regional differences in cortical
>>> organization between healthy controls and patients for which i am using
>>> VBM,  For spatial registration of 50 HCP subjects i would like to know if
>>> HCP offers some customized templates for registration or do i have to
>>> perform affine transformation and non linear registration, please kindly
>>> let me know .
>>>
>>>
>>>
>>>
>>> Thanks
>>> Vasudev
>>>
>>> _______________________________________________
>>> HCP-Users mailing list
>>> [email protected]
>>> http://lists.humanconnectome.org/mailman/listinfo/hcp-users
>>>
>>>
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>>
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>>
>> The materials in this message are private and may contain Protected
>> Healthcare Information or other information of a sensitive nature. If you
>> are not the intended recipient, be advised that any unauthorized use,
>> disclosure, copying or the taking of any action in reliance on the contents
>> of this information is strictly prohibited. If you have received this email
>> in error, please immediately notify the sender via telephone or return mail.
>>
>
>

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