Dear Sir,

Now i have obtained 30 Healthy controls from the same scanner along with 50
subjects with Bilateral Vestibulopathy , I would like to use HCP pipelines
for 1. Batch processing and also i would like to investigate the
voxel-based cortical thickness ( as opposed to VBM , as you have cited in
earlier mails ), could you please let me know how could i perform
voxel-based cortical thickness, could you please suggest me some methods.



Thanks
Vasudev

On 22 June 2016 at 15:51, Harms, Michael <[email protected]> wrote:

>
> Hi,
> No, we don’t have any such phantom measurements available.  And there are
> a lot more issues at play in terms of differences between scanners than
> just differing magnetic inhomogeneities anyway.
>
> cheers,
> -MH
>
> --
> Michael Harms, Ph.D.
> -----------------------------------------------------------
> Conte Center for the Neuroscience of Mental Disorders
> Washington University School of Medicine
> Department of Psychiatry, Box 8134
> 660 South Euclid Ave. Tel: 314-747-6173
> St. Louis, MO  63110 Email: [email protected]
>
> From: Dev vasu <[email protected]>
> Date: Wednesday, June 22, 2016 at 1:03 AM
>
> To: "Harms, Michael" <[email protected]>
> Cc: "[email protected]" <[email protected]>
> Subject: Re: [HCP-Users] Spatial normalization of 50 Subjects T1w images
>
> Dear sir,
>
>
> In order to avoid magnetic homogenities of different scanners, can i take
> into consideration Field maps from HCP data and   some Phantom measurements
> ( like ACR Phantom Measurements ) ?, If so does HCP provides data for
> Phantom Measurements ?.
>
>
>
> Thanks
> Vasudev
>
> On 21 June 2016 at 21:53, Harms, Michael <[email protected]> wrote:
>
>>
>> Hi,
>> I’m sorry, but there is no way to model or account for the effect of
>> possible scanner differences if you don’t have at least some of each group
>> of subjects collected on each scanner.  In your current situation, you have
>> no mechanism to attempt to disentangle the effects of vestibulopathy vs.
>> scanner.
>>
>> cheers,
>> -MH
>>
>> --
>> Michael Harms, Ph.D.
>> -----------------------------------------------------------
>> Conte Center for the Neuroscience of Mental Disorders
>> Washington University School of Medicine
>> Department of Psychiatry, Box 8134
>> 660 South Euclid Ave. Tel: 314-747-6173
>> St. Louis, MO  63110 Email: [email protected]
>>
>> From: Dev vasu <[email protected]>
>> Date: Tuesday, June 21, 2016 at 2:36 PM
>>
>> To: "Harms, Michael" <[email protected]>
>> Cc: "[email protected]" <[email protected]>
>> Subject: Re: [HCP-Users] Spatial normalization of 50 Subjects T1w images
>>
>> Dear Sir,
>>
>> The vestibulopathy subject scans are from scanner outside HCP, we here in
>> LMU Munich use Siemens Skyra 3T scanner, in such case how to neutralize or
>> eliminate the differences which may occur due to scanner differences ?.
>>
>>
>> Thanks
>> Vasudev
>>
>>
>> On 21 June 2016 at 21:29, Harms, Michael <[email protected]> wrote:
>>
>>>
>>> Hi,
>>> I would use a measure that relates in a concrete way to the underlying
>>> neuroanatomy, such as cortical thickness.
>>>
>>> There may be a bigger issue here, which is that I’m now guessing that
>>> your vestibulopathy subjects are coming from scans collected from outside
>>> HCP?  If so, you have a major confound, because you will be attempting to
>>> compare two groups that were collected on completely different scanners.
>>> In which case, any difference you find could be attributed to just scanner
>>> difference effects.
>>>
>>> cheers,
>>> -MH
>>>
>>> --
>>> Michael Harms, Ph.D.
>>> -----------------------------------------------------------
>>> Conte Center for the Neuroscience of Mental Disorders
>>> Washington University School of Medicine
>>> Department of Psychiatry, Box 8134
>>> 660 South Euclid Ave. Tel: 314-747-6173
>>> St. Louis, MO  63110 Email: [email protected]
>>>
>>> From: <[email protected]> on behalf of Dev vasu <
>>> [email protected]>
>>> Date: Tuesday, June 21, 2016 at 2:02 PM
>>> To: "Harms, Michael" <[email protected]>
>>> Cc: "[email protected]" <[email protected]>
>>> Subject: Re: [HCP-Users] Spatial normalization of 50 Subjects T1w images
>>>
>>> Dear Professor,
>>>
>>> I was advised to do VBM, I understand questions pertaining to
>>> biological  validity of VBM and interpretation issues. I would like to
>>> investigate the cortical regional differences between health controls and
>>> controls with vestibulopathy , If you have any other suggestion pertaining
>>> to this task i would really appreciate your response.
>>>
>>>
>>>
>>> Thanks
>>> Vasudev
>>>
>>> On 21 June 2016 at 20:47, Harms, Michael <[email protected]> wrote:
>>>
>>>> Hi,
>>>> If I may, why VBM?  VBM is prone to a number of interpretational
>>>> issues, as opposed to say cortical thickness, which is already available
>>>> for you as part of the HCP processing.
>>>>
>>>> cheers,
>>>> -MH
>>>>
>>>> --
>>>> Michael Harms, Ph.D.
>>>> -----------------------------------------------------------
>>>> Conte Center for the Neuroscience of Mental Disorders
>>>> Washington University School of Medicine
>>>> Department of Psychiatry, Box 8134
>>>> 660 South Euclid Ave. Tel: 314-747-6173
>>>> St. Louis, MO  63110 Email: [email protected]
>>>>
>>>> From: <[email protected]> on behalf of Dev vasu <
>>>> [email protected]>
>>>> Date: Tuesday, June 21, 2016 at 1:30 PM
>>>> To: Stamatios Sotiropoulos <[email protected]>, "
>>>> [email protected]" <[email protected]>,
>>>> "Glasser, Matthew" <[email protected]>, Timothy Brown <
>>>> [email protected]>
>>>> Subject: [HCP-Users] Spatial normalization of 50 Subjects T1w images
>>>>
>>>> Dear Sir ,
>>>>
>>>>
>>>> I am using HCP data ( 50 subjects ) + 50 patients with bilateral
>>>> vestibular paresis to examine the Regional differences in cortical
>>>> organization between healthy controls and patients for which i am using
>>>> VBM,  For spatial registration of 50 HCP subjects i would like to know if
>>>> HCP offers some customized templates for registration or do i have to
>>>> perform affine transformation and non linear registration, please kindly
>>>> let me know .
>>>>
>>>>
>>>>
>>>>
>>>> Thanks
>>>> Vasudev
>>>>
>>>> _______________________________________________
>>>> HCP-Users mailing list
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>>>> http://lists.humanconnectome.org/mailman/listinfo/hcp-users
>>>>
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>>>> mail.
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>>>
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