Hi, HCP Users and Developers.

We have been trying to build a protocol for BOLD and DWI on our Skyra
(VE11C) using the latest release of HCP pulse sequences. But we
haven't been completely successful with what we wanted to achieve.

A) BOLD: We were hoping to get a TR in the range of 750ms, res = 2mm3, echo
spacing (ES) approx 0.65. We were able to get to echo spacing of 0.69 and
all the other parameters with MB = 8. However, the sequence doesn't run and
it gives us "Max amplitude overflow on gradient z axis" after MB factor
exceeds 2.  It appears to me that then we have to sacrifice TR and only run
with MB = 2. Is there anybody with a Skyra who has able to achieve what we
are hoping for and willing to share the protocol with us? OR if somebody
could guide us to resolve the error of amplitude overflow.

B) DWI: The idea was to have res = 1.5mm3, 2b-values at 1000 and 2500, 64
directions with the best BW and ES achievable. The sequence runs for 7
minutes out of total 13 minutes and gives gradient power amplifier error.
On Michael Harms's suggestion, I adjusted flip angle to 78/160 at a TR of
5500 ms with excite/refocus pulse duration of 3840 and 7680. there was a
pop up warning that RF is clipped and the maximum refocusing angle was 142
instead of 160. I placed a 64 directions diffusion vector and ran the
sequence under "free" mode. Again, I will appreciate if  there is anybody
with a Skyra who has able to achieve what we are hoping for and willing to
share the protocol with us, along with the diffusion vector sets? OR if
somebody could guide us to resolve the error.

Thank you.

Regards

--VM

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