Hi,
There are differing opinions on the appropriateness of MGTR at the present time 
(pending future alternatives).  You may be interested in the following recent 
paper from Murphy and Fox:
https://www.ncbi.nlm.nih.gov/pubmed/27888059

And, if you want to see some data on the effects of using it vs. not using it 
in HCP data specifically, you can see the following paper:

http://www.ncbi.nlm.nih.gov/pubmed/27571276


cheers,

-MH


--
Michael Harms, Ph.D.
-----------------------------------------------------------
Conte Center for the Neuroscience of Mental Disorders
Washington University School of Medicine
Department of Psychiatry, Box 8134
660 South Euclid Ave. Tel: 314-747-6173
St. Louis, MO  63110 Email: [email protected]

From: 
<[email protected]<mailto:[email protected]>>
 on behalf of "Glasser, Matthew" <[email protected]<mailto:[email protected]>>
Date: Thursday, January 5, 2017 at 11:50 AM
To: Joelle Zimmermann 
<[email protected]<mailto:[email protected]>>, Stephen 
Smith <[email protected]<mailto:[email protected]>>
Cc: "[email protected]<mailto:[email protected]>" 
<[email protected]<mailto:[email protected]>>
Subject: Re: [HCP-Users] global signal regression on HCP ICA FIX denoised BOLD?

This is at your discretion, but we don’t typically recommend it.  We are 
working on a better solution for global physiological noise that doesn’t 
replace a positive bias in correlations with a negative one.  Another 
alternative that avoids the issue is to use partial correlation.

Peace,

Matt.

From: 
<[email protected]<mailto:[email protected]>>
 on behalf of Joelle Zimmermann 
<[email protected]<mailto:[email protected]>>
Date: Thursday, January 5, 2017 at 12:47 PM
To: Stephen Smith <[email protected]<mailto:[email protected]>>
Cc: "[email protected]<mailto:[email protected]>" 
<[email protected]<mailto:[email protected]>>
Subject: Re: [HCP-Users] global signal regression on HCP ICA FIX denoised BOLD?

Thanks Stephen. Was there GSR done on the HCP data at any point for the 
non-denoised version?

If I wanted to do GSR myself on the HCP data, are there any recommendations 
that the HCP group has? Or global signal regressors that have been already 
processed? Or is this something that is at the discretion of each researcher 
afterwards?

On Thu, Jan 5, 2017 at 12:00 PM, Stephen Smith 
<[email protected]<mailto:[email protected]>> wrote:
Yes,.
Cheers.


On 5 Jan 2017, at 11:57, Joelle Zimmermann 
<[email protected]<mailto:[email protected]>> wrote:

Hi HCPers,

Is it correct that global signal regression was not done on the ICA FIX 
denoised fmri BOLD data?

Thanks,
Joelle

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