I would do the second option if only to conserve space and computational burden.

Peace,

Matt.

From: 
<[email protected]<mailto:[email protected]>>
 on behalf of Aaron C <[email protected]<mailto:[email protected]>>
Date: Saturday, January 14, 2017 at 12:12 PM
To: "[email protected]<mailto:[email protected]>" 
<[email protected]<mailto:[email protected]>>
Subject: [HCP-Users] A question about calculating dense connectome for 
individual subject


Dear HCP experts,


I have a question about calculating dense connectome for individual subject 
using HCP resting-state data. Should I calculate a dense connectome for each 
run of the subject and then average them? Or, should I demean, variance 
normalize, and concatenate the four runs and then calculate a dense connectome 
for the subject? Thank you.

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