Hi Matt,

I appreciate your help with working through ICA using HCP data. Following
your recommendation, I converted CIFTI files to NIFTI and am trying to run
through ICA, but I am still experiencing problems.

Running ICA for 62 participants (rest1_RL session) on a high power
computing server with 72 GB mem and a time limit of 5 days, the ICA times
out, and cannot pass the first stage of removing the mean image and
normalizing by the voxel-wise variance. This is the script I'm using:
melodic -i /projects/niblab/scripts/twin/input_ica.txt --migp --sep_vn -o
/projects/niblab/scripts/twin/ica_out -v --nobet --bgthreshold=10 --tr=1 -d
50 --report --mmthresh=0.5 --Oall

>From your experience, should we expect ICA to take 5+ days to run, or is
there a way to speed this up?

Thanks for your help!
Jenny

On Tue, Mar 7, 2017 at 3:48 PM, Glasser, Matthew <[email protected]> wrote:

> Hi Jenny,
>
> Indeed you can use wb_command -cifti-convert -to-nifti to convert the
> files to NIFTI, run melodic, do dual regression, etc, and then when you
> have your output maps, you convert them back to CIFTI with wb_command
> -cifti-convert -from-nifti and view them in Workbench.  The only thing to
> keep in mind is that spatial relationships will not be 3D volumetric in
> these converted CIFTI files, so things like smoothing would not be
> appropriate to do on them.  ICA or dual regression doesn’t use spatial
> neighborhood information (though you will need to select your own ICA
> dimensionality).
>
> Peace,
>
> Matt.
>
> From: Jenny Gilbert <[email protected]>
> Date: Tuesday, March 7, 2017 at 2:08 PM
> To: Matt Glasser <[email protected]>
>
> Subject: Re: [HCP-Users] ICA failure with volumetric ICA-FIX denoised
> files
>
> Hi Matt,
>
> Thanks for your help! How do I complete ICA the CIFTI MSMAII files? Is the
> first step to convert the files to NIFTI format in workbench? Also, I
> planned to complete dual regression with the ICA generated components, so
> how does dual regression work with CIFTI format data? Can all of this be
> done by converting CITFI to NIFTI, and then running the usual commands? I'm
> new to workbench, and would love all the help that you experts can offer!
>
> Thank you so much!
> Jenny
>
> On Tue, Mar 7, 2017 at 2:05 PM, Glasser, Matthew <[email protected]>
> wrote:
>
>> I think there is a bug in melodic, which I also encountered.  I would
>> report this to the FSL list, but it is likely the issue will be fixed in
>> the next FSL release.
>>
>> Also, if you are running melodic in the volume and combining across
>> subjects, this is not recommended because much of the brain is not well
>> aligned in the volume.  It is instead recommended that you use the CIFTI
>> data that has been aligned with MSMAll.  ICA gives very different results
>> depending on whether the data are well aligned or not.
>>
>> Peace,
>>
>> Matt.
>>
>> From: <[email protected]> on behalf of Kajsa
>> Igelström <[email protected]>
>> Date: Tuesday, March 7, 2017 at 12:40 PM
>> To: "[email protected]" <[email protected]>
>> Subject: Re: [HCP-Users] ICA failure with volumetric ICA-FIX denoised
>> files
>>
>> Hi Jenny and others!
>> I'm also unable to run these files through Melodic. The most common
>> problem is that it doesn't converge, and under some circumstances it seems
>> like Melodic just stops in the middle of normalizing individual files, at
>> points that are not logical to me, or reproducible.
>> Best,
>> Kajsa
>>
>>
>>
>> On Tue, Mar 7, 2017 at 12:24 PM, Jenny Gilbert <[email protected]>
>> wrote:
>>
>>> Hello HCP!
>>>
>>> I am trying to complete ICA using the volumetric ICA-FIX de noised data
>>> (rfMRI_REST1_RL_hp2000_clean.nii.gz files), and melodic keeps failing.
>>> It looks like melodic gets hung up on some participants cannot progress
>>> while removing the mean image and normalizing by the voxel-wise variance.
>>>
>>> Has anyone come across this same problem? Any advice on how to fix?
>>>
>>> Thank you!
>>> Jenny
>>> _______________________________________________
>>> HCP-Users mailing list
>>> [email protected]
>>> http://lists.humanconnectome.org/mailman/listinfo/hcp-users
>>>
>>
>> _______________________________________________
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>>
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>
>
>
> --
> *Jenny Gilbert*
> [email protected] | 443.846.3687 <(443)%20846-3687>
>
>
> ------------------------------
>
> The materials in this message are private and may contain Protected
> Healthcare Information or other information of a sensitive nature. If you
> are not the intended recipient, be advised that any unauthorized use,
> disclosure, copying or the taking of any action in reliance on the contents
> of this information is strictly prohibited. If you have received this email
> in error, please immediately notify the sender via telephone or return mail.
>



-- 
*Jenny Gilbert*
[email protected] | 443.846.3687

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