I don’t think you can use HCP data as a control group.  You would need to 
acquire control data similar to the patient data.

Peace,

Matt.

From: Zhan Yafeng <[email protected]<mailto:[email protected]>>
Date: Monday, May 22, 2017 at 7:49 PM
To: Matt Glasser <[email protected]<mailto:[email protected]>>
Subject: Re: [HCP-Users] help

Hi Matt,

I have collected some patient data and want to use HCP data as control group. 
Does it affect the result if I use different preprocessing procedure (the 
preprocessing as you suggested) between different subjects?

Thank you a lot.

Best,
Yafeng

From: Glasser, Matthew [mailto:[email protected]]
Date: 2017年5月23日 0:33
To: Zhan Yafeng; 
[email protected]<mailto:[email protected]>
Subject: Re: [HCP-Users] help

While it would definitely be beneficial to map your data onto the cortical 
surface, two aspects of your acquisition will make it difficult to use the HCP 
Pipelines in their current state:

  1.  Low resolution T2w scan (at 2.5mm) will make generation of myelin maps 
and using the T2w to help surface placement be problematic.
  2.  Lack of a field map will make accurate registration between fMRI and T1w 
data problematic.  Using an average field map of similar subjects scanned on 
the same scanner will deal with most but not all of the distortions.  We don’t 
currently have a module for using an average field map, though perhaps someone 
on the list has done this.
It might make the most sense to do your processing outside of the HCP Pipelines 
(e.g. just standard FreeSurfer recon-all and your standard individual subject 
fMRI preprocessing without spatial smoothing) and then map the fMRI data onto 
individual cortical surfaces similar to how it is done in the fMRISurface 
pipeline module.

Peace,

Matt.

From: 
<[email protected]<mailto:[email protected]>>
 on behalf of Zhan Yafeng 
<[email protected]<mailto:[email protected]>>
Date: Monday, May 22, 2017 at 4:36 AM
To: "[email protected]<mailto:[email protected]>" 
<[email protected]<mailto:[email protected]>>
Subject: [HCP-Users] help

Dear HPC experts,

Can I use HCP pipeline to process my own resting state fMRI data which has 
lower resolution (rs-fMRI: TR=2000ms, voxel size=3.75x3.75x4; T1: voxel 
size=1x1x1; T2: voxel size=0.94x0.94x2.5) than HCP data?
We did not collect either a standard gradient echo field map or a spin echo 
field map, can I get the averaged field map from a different set of subjects 
with different voxel size as the rs-fMRI which collected from a different 
scanner?
Thanks in advance.

Regards,
Yafeng

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