Hi Jodi,

Yes, only the unadjusted scores are available in the negative affect, 
psychological well-being, social relationships, and stress and self-efficacy 
domains from Toolbox. There is no set formula for converting between unadjusted 
scores and the age- or fully-adjusted scoring for NIH Toolbox, so you will need 
to use the unadjusted scores.


See the NIH Toolbox Scoring and Interpretation Guide from 2012 (link to the PDF 
on Box)<https://wustl.box.com/v/2012-NIHToolboxScoringManual> when the HCP 
protocol was set, especially p. 3-4 for a description of the Unadjusted scale 
scores for patient recorded outcomes (PRO) measures, including the domains you 
mentioned. Basically, the Unadjusted scores can be considered T-scores with a 
mean of 50 and a SD of 10 across the entire Toolbox normative sample, 
unadjusted for age, race, or any other variable. For interpretation of specific 
variables see the descriptions from p.30 onward.


Best,

Jenn

Jennifer Elam, Ph.D.
Scientific Outreach, Human Connectome Project
Washington University School of Medicine
Department of Neuroscience, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387<tel:314-362-9387>
[email protected]<mailto:[email protected]>
www.humanconnectome.org<http://www.humanconnectome.org/>


________________________________
From: Gilman, Jodi <[email protected]>
Sent: Thursday, February 22, 2018 8:54:19 AM
To: Elam, Jennifer; [email protected]
Cc: Manghis, Eve M.
Subject: NIH toolbox measures

Hi Jenn,

I have a question about the scores from NIH toolbox on the domains of negative 
affect, psychological well-being, social relationships, and stress and 
self-efficacy.

I see that the scores available for download are all unadjusted; I do not see a 
column for any adjusted scores on these measures.

Would you recommend using the unadjusted scores? Or, is there a formula to 
adjust them?

The NIH Toolbox scoring PDF states: "For the NIH Toolbox General Life 
Satisfaction Survey, higher scores are indicative of more general life 
satisfaction. Scores 1 SD or more below the mean (T ≤ 40) suggest low levels of 
general life satisfaction and scores 1 SD or more above the mean (T ≥ 60) 
suggest high level”

Is this true for unadjusted as well?

Thanks,
Jodi

Jodi Gilman, Ph.D.
Assistant Professor, Harvard Medical School
Center for Addiction Medicine
Massachusetts General Hospital
101 Merrimac St.
Boston, MA 02114
Tel.:    617-643-7293
Fax:    617-643-1998


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