>I'm getting this error processing string (below) for any mail messages sent
>from my server to this ISP.  I and my various virtual domain users can send
>and receive just fine to everyone but these guys.

then these guys have a mail failure

>As part of a buyout of a buyout (Onemain bought Lightspeed, which in turn
>got bought by Earthlink) there has been an infrastructure change in the mail
>system at that ISP.  Otherwise, all I know is they say the problem is my
>fault.

The 451 response code is from them. SMTP failure is Imail logging the loss 
of connectivity to them. they hung up on you

Check your DNS records for you mail server and any domain. all must have A 
and MX records.

Len

http://MenAndMice.com/DNS-training
http://BIND8NT.MEIway.com : ISC BIND 8.2.4 for NT4 & W2K
http://IMGate.MEIway.com  : Build free, hi-perf, anti-abuse mail gateways


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