http://www.smh.com.au/national/health/grieving-hearts-can-be-deadly-says-study-20120325-1vso1.html

Grieving hearts can be deadly, says study 
Richard Gray
March 26, 2012 
  a.. 
 
Heartaches ... there's a biological reason why old married couples sometimes 
die within a few days of each other. 



IT REALLY is possible to die of a ''broken heart'', according to research that 
has revealed how bereavement can weaken the body's ability to fight infections.

Scientists found the emotional stress of losing a loved one could lead to parts 
of the immune system being suppressed, leaving grieving relatives more 
vulnerable to infections from bacteria. The findings could help explain cases 
of widows and widowers who die soon after their spouse.

Lord Callaghan, the former British prime minister, died of pneumonia aged 92 in 
2005, just 11 days after Audrey, his wife of 67 years.

Johnny Cash died of complications related to diabetes while in hospital in 2003 
at the age of 71. It was said at the time that he had been left weakened by the 
grief of losing his wife June, 73, three months earlier.

Immunologists at the University of Birmingham found increased stress levels and 
depression brought on by grief could interfere with the function of a type of 
white blood cell known as neutrophils, which are responsible for fighting 
bacterial infections such as pneumonia.

The impact became more profound in older adults because they had lost the 
ability to produce a hormone to counteract this dampening affect, meaning even 
healthy elderly people could fall victim to disease.

Janet Lord, who led the research, said: ''There are a lot of anecdotes about 
couples who were married for 40 years when one of them passes away and then the 
other dies a few days later. It seems there is a biological basis for this. 
Rather than dying of a broken heart, however, they are dying of a broken immune 
system. They usually get infections.''

The researchers studied the immune systems and hormone levels of 48 healthy 
adults aged 65 and over. Half of the group had suffered a major bereavement in 
the past year. They found the antibacterial action of neutrophils in grieving 
participants was significantly reduced compared with those who had not suffered 
a bereavement. The bereaved also had raised levels of the stress hormone 
cortisol.

The researchers also found that suffering a hip fracture could lead to the same 
hormone imbalance. This could explain why about a quarter of people over 80 die 
within a year of suffering a hip fracture.

The Telegraph, London


Read more: 
http://www.smh.com.au/national/health/grieving-hearts-can-be-deadly-says-study-20120325-1vso1.html#ixzz1qFnMYeFD


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