Hi Paolo - just cc'ing the dev list so we all have a record of the emails!

On 30/03/2012 10:35, Paolo Di Tommaso wrote:
>
> T-Coffee can produce the alignment score in a text file, like this
>
> http://tcoffee.crg.cat/data/79609a4a/sh3.score_ascii
OK.
>
> Merging this information with the resulting sequence alignment, should 
> not be too difficult to visualize the resulting color scheme in Jalview.
yes.
>
> In my opinion there are two main use cases:
>
> 1)  The users (or the developer in the case of the applet) provide the 
> sequences alignment and the score ascii files as produced by T-Coffee. 
> Jalview manage to convert the scores in its internal structures and 
> render the alignment using the associated color scheme.
>
>
> 2) The user submits a T-Coffee alignment request. The web service send 
> back the score ascii other than the alignment fasta file, and then the 
> case fallback to the previous one.
>
>
> At the beginning I would focus on the most simple scenario (which by 
> accident is the one on which I'm more interested :)), I mean the 
> Jalview applet version and make it able to render the colored T-Coffee 
> alignment, adding an extra parameter to specify the generated 
> score_ascii to the applet.
>
>
> What do you think about that?
I think it sounds great. The TCoffee scores fall into a similar class as 
JNet scores - which get turned into alignment annotation and can be 
specified separately to the alignment. Extending the web service will 
require a bit more familiarity with Jalview's code, so I'd definitely 
suggest #1 is the place to start.

Jim.
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