My question pdb files which contain alpha-carbons only ... like 1alm.pdb

Q: Is it possible to calculate a vector which is orthogonal to the
backbone if one is only given a chain of alpha-carbons?

To draw backbones/traces, we only need the alpha carbon positions.

In order to draw ribbons/strands/cartoons, we need to calculate an
orthogonal vector that points to the edge of the ribbon.

When the entire NCCO amino acid backbone is present then the relative
position of the carbonyl oxygen is used to calculate this vector.

In a helix structure, one could calculate such a vector by using the angle
formed by three successive alpha carbons. It is not clear to me whether or
not the same thing would work in other structures.

If someone wants to read up on this, the following paper seems to do some
useful and related types of calculations:

Micheal Levitt and Jordon Greer, 1977
Automatic identification of secondary structure in globular proteins
http://csb.stanford.edu/levitt/Levitt_JMB77_Secondary_structure.pdf


Miguel




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