Nicolas wrote:

> Hi,
>
> I looked at RasMol Manual and found this :
>
> Structure
>
> Syntax:  structure
> The RasMol 'structure' command calculates secondary structure assignments
> for the currently loaded protein. If the original PDB file contained
> structural assignment records (HELIX, SHEET and TURN) these are discarded.
> Initially, the hydrogen bonds of the current molecule are found, if this
> hasn't been done already. The secondary structure is then determined using
> Kabsch and Sander's DSSP algorithm. Once finished the program reports the
> number of helices, strands and turns found.
>
>
> Seems to be what we are looking for.

Nicolas,

They are looking for something at a lower level than this.

The RasMol documentation above refers to the identification of protein
secondary structures from a .pdb file that does not contain structure
records for HELIX, SHEET, and TURN. However, it assumes that it is a .pdb
file that already has the amino acid residues defined.

The structure detection that is needed for FAH is at a level below this.
The .xyz files do not have the amino acids identified. Therefore, we would
need code which identifies amino acids from individual atoms & their
bonds.

I am sure that this is an interesting problem and that people have worked
on it. It is essentially a pattern match on sub-structures.

It seems to me that it is the kind of thing that warrants a literature
search prior to starting in on an implementation. It also seems to me that
it would be a great project for a graduate student.



Miguel



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