On Sunday 06 February 2005 10:08 pm, Miguel wrote:
> Nicolas wrote:
> > I looked at RasMol Manual and found this :
> >
> > Syntax:  structure
> > The RasMol 'structure' command calculates secondary structure assignments
> > for the currently loaded protein. If the original PDB file contained
> > structural assignment records (HELIX, SHEET and TURN) these are
> > discarded. Initially, the hydrogen bonds of the current molecule are
> > found, if this hasn't been done already. The secondary structure is then
> > determined using Kabsch and Sander's DSSP algorithm. Once finished the
> > program reports the number of helices, strands and turns found.
> >
> > Seems to be what we are looking for.
>
> They are looking for something at a lower level than this.
>
> The RasMol documentation above refers to the identification of protein
> secondary structures from a .pdb file that does not contain structure
> records for HELIX, SHEET, and TURN. However, it assumes that it is a .pdb
> file that already has the amino acid residues defined.
>
> The structure detection that is needed for FAH is at a level below this.
> The .xyz files do not have the amino acids identified. Therefore, we would
> need code which identifies amino acids from individual atoms & their
> bonds.

Correct. What I was asking about was *primairy* structure detection.

> I am sure that this is an interesting problem and that people have worked
> on it. It is essentially a pattern match on sub-structures.
>
> It seems to me that it is the kind of thing that warrants a literature
> search prior to starting in on an implementation. It also seems to me that
> it would be a great project for a graduate student.

Egon


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