On Thursday 13 July 2006 16:07, Bob Hanson wrote:
> Sounds like I should just hold off on this and see what comes of Miguel
> Rojas's work.

Miguel is mostly done, I think.

> Can you summarize for me how the CDK, Bioeclipse, and Jmol fit together?

Please download Bioclipse 0.9.2 and see for your self (1.0 will be released 
next week.) Start it, and do Window -> Show View -> Other -> Jmol View.

Bioclipse is a workbench for chemoinformatics and bioinformatics. See the 
bioclipse website to see where things are going. 

> Which parts of Jmol are utilized? 

Jmol is used for what Jmol is good at: scriptable visualisation. Jmol IO is 
currently not used, but this could be enabled.

> Which parts are replaced with the CDK version?

There is nothing really replaced, though you might consider reading files as 
such.

The CDK library (and possibly *any* other library) is used as backend for 
doing chemoinformatics stuff, just like it uses BioJava for sequence stuff. 
For example, I am supervising a summer student who is working on integration 
of ghemical via JNI, so Bioclipse will be able to calculate QM properties 
too. Since Jmol is the visualizer we use right now for 3D molecular content, 
Jmol is used for rendering the optimized structure.

In case of partial charges, the CDK plugin would hook in a 'calculate charges' 
action for the molecular resources so that one could open a XYZ file, and 
then calculate partial charges with the CDK plugin, and visualize it on top 
of a surface shown in the Jmol View.

Check out my latest blog on the Jmol View with 'context help' refering to a 
static copy of your command reference:

  http://chem-bla-ics.blogspot.com/2006/07/context-help-in-bioclipse.html

The Jmol plugin also provides (sorry for repeating myself for the second 
time), a Jmol script file editor, with syntax highlighting and 
autocompletion. So, just type 'cart' press Ctrl^Space and pick 'cartoon' from 
the popup list :) (No, it does not give the full syntax yet.) And run this 
resource by simply clicking the 'run' button in the toolbar.

Lot's of possibilities. With respect to the current application (and I'm sure 
I've posted this too before), only the AtomSetChooser is really missing at 
this moment...

Egon

-- 
CUBIC
blog: http://chem-bla-ics.blogspot.com/


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