G'day, Eddy here.
 
Kathie mentioned:-
<<<< But, there are also breeders of both mixes and purebreds who are very concerned with COI. >>>>
 
 
Yes there are some breeders who are very concerned with COI, and you may even find some pet owners who are similarly concerned.
 
Coefficient of Inbreeding (COI) is a complex formula for accessing the degree of commonality within a pedigree, it is largely believed by most geneticists that a high COI is detrimental for any breed as it can and does have an effect on the immune system and also the ability to reproduce, also increases chances for other hereditary based diseases. The next question is what is an "upper acceptable limit" and this could vary from breeder to breeder, and one does encounter the use of very high COI's say in a brother sister mating or father daughter mating. BUT realise that in determining COI one does not just calculate the COI for a couple of generations but one MUST include the impact from quite a number of matings from previous generations even back to 10 generations.
 
Determining COI is a bit complex and I suggest this website might be of help, see at this address:-
http://www.geocities.com/willowind_dals/
As this website has a high volume of internet traffic at times it might not be available as it exceeds YahooGeocities bandwidth requirements, if so just try again later on.
 
This site has a number of very interesting documents as well as a program for pedigrees, and also a program for calculating COI based on pedigrees from 5-10 generations. These 2 programs work together to make life simpler, and the more generations you have imputed then the more accurate is the COI results.
 
By the way, the creator of these 2 programs mentions this which I think is really great:-
"This program is not "shareware" or "freeware," it is "hugware." If you like the program and want to continue using it, then give your Dal a hug. If you don't have a Dal, give your neighbor's Dal a hug. If your neighbor doesn't have a Dal, then give any pooch a hug."
 
Eddy Safianski
Sale Victoria. Australia
Email:- [EMAIL PROTECTED]
Website:-
http://members.optusnet.com.au/~safcav/
...

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