CMD + F5,  will toggle voiceover off/on.
This will neither fix muted speech or muted system volume.

- Brad -

On Nov 16, 2025, at 08:18, 'Emma May' via MacVisionaries 
<[email protected]> wrote:

Hi there should already bye one. It is command f 5 but also if your keyboard 
is like mine from the top line from the very right there is the on off and 
touch finger button, then volume up then volume down and then volume mute. Hope 
that helps love emma

> On 16 Nov 2025, at 14:02, Paul Hopewell <[email protected]> wrote:
> 
> I am running the latest Ventura on my 1997 iMac. I cannot see the screen and 
> so am totally reliant on VoiceOver.
> Can I set up a keyboard shortcut to toggle speech on and off, like the 3 
> finger double tap on IOS?
> Ocasionally speech becomes muted by hitting the wrong keyboard keys and I 
> have to seek sighted help to get VO working again.
> I recall setting up such a keyboard shortcut in the past but I seem to have 
> deleted it.
> Many thanks … Paul Hopewell
> 
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