Hello Franz, thanks for reporting this. You are not the only person
experiencing this issue with Mauve 2.4.0. It looks like a bug! I am
planning to take a close look and work on a fix just as soon as
Australian grant-writing deadlines pass in a couple weeks.

Best,
-Aaron

On Tue, 2015-02-10 at 16:22 +0100, Franz Baumdicker wrote:
> Hi,
> 
> I am trying to align the core genes (~1000 genes) of 41 small bacterial 
> genomes. However, depending on the input order I am getting a lot of 
> scoring error messages or no errors.
> Unfortunately I didn't find an input order for all 41 genomes which 
> produces no errors.
> In addition I found two sequence files where even
> progressiveMauve --output=outfile seq1.faa seq2.faa
> produces scoring errors while
> progressiveMauve --output=outfile seq2.faa seq1.faa
> does not.
> 
> I am using version 2.4.0 on Linux. In version 2.3.1 no scoring errors 
> show up, but progressiveMauve gets caught in an endless loop for the 
> same input orders.
> 
> What does scoring error mean?
> Is there any way to predict which order of sequences will produce 
> scoring errors and which doesn't?
> Or even better is there a way to modify the input data to prevent the 
> scoring error at all?
> 
> Greetings,
> 
> Franz Baumdicker
> 
> -------
> Dr. Franz Baumdicker
> Math. Institut
> Eckerstr 1
> 79106 Freiburg
> 
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-- 
Aaron E. Darling, Ph.D.
Associate Professor, ithree institute
University of Technology Sydney
Australia

http://darlinglab.org
twitter: @koadman





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Dive into the World of Parallel Programming. The Go Parallel Website,
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look and join the conversation now. http://goparallel.sourceforge.net/
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