Dear all,
This may have been asked before (maybe by me), but does anyone have any good 
advice on how to disrupt GST self-association?  I often have trouble with 
preps. of GST-fusion proteins (when I need the intact fusion protein) being 
contaminated with GST that is very difficult to get rid of.  I think this may 
be a result of "free" GST associating tightly with the GST-fusion.  Has anyone 
else had this problem, and solved it?

Many thanks,

Paul Phelan
Tufts University
Boston

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