FWIW. I have created:

* https://github.com/GrahamDumpleton/mod_wsgi/issues/260 
<https://github.com/GrahamDumpleton/mod_wsgi/issues/260>

to have it use value of $TMPDIR rather than /tmp. On MacOS that should result 
in special directory down under /var/tmp being used and cron shouldn't delete 
it.

Graham

> On 23 Jan 2018, at 8:21 pm, Graham Dumpleton <graham.dumple...@gmail.com> 
> wrote:
> 
> Use the --server-root option to have the files generated by mod_wsgi-express, 
> generated into a directory other than under /tmp.
> 
> On some system setups, cron jobs exist that will delete files under /tmp that 
> are older than a certain date. This can cause the failure.
> 
> Graham
> 
>> On 23 Jan 2018, at 8:17 pm, Teemu Korpijaakko <tko...@gmail.com 
>> <mailto:tko...@gmail.com>> wrote:
>> 
>> We're having an issue with a Flask application running under 
>> mod_wsgi-express on a Mac mini.  2 of them actually and they both have the 
>> same issue.  The application runs fine for a while (a week or a few days) 
>> and then users see a Forbidden message.  We then have to kill apache and 
>> restart it using flask/bin/mod_wsgi-express start-server --port 5000 
>> ./wsgi.py &.  It starts up fine and runs until the next failure.  The 
>> error_log looks like this prior to failure:
>> 
>> 
>> 
>> [Tue Jan 23 06:56:02.435292 2018] [access_compat:error] [pid 7740] [client 
>> 192.168.100.5:57279] AH01797: client denied by server configuration: 
>> /tmp/mod_wsgi-localhost:5000:501/htdocs 
>> 
>> [Tue Jan 23 06:56:28.573308 2018] [access_compat:error] [pid 7609] [client 
>> 192.168.100.5:57280] AH01797: client denied by server configuration: 
>> /tmp/mod_wsgi-localhost:5000:501/htdocs 
>> 
>> [Tue Jan 23 06:57:13.220948 2018] [access_compat:error] [pid 7740] [client 
>> 192.168.100.5:57282] AH01797: client denied by server configuration: 
>> /tmp/mod_wsgi-localhost:5000:501/htdocs 
>> 
>> [Tue Jan 23 06:57:15.918491 2018] [access_compat:error] [pid 7609] [client 
>> 192.168.100.5:57283] AH01797: client denied by server configuration: 
>> /tmp/mod_wsgi-localhost:5000:501/htdocs 
>> 
>> [Tue Jan 23 06:57:35.765019 2018] [mpm_prefork:notice] [pid 5343] AH00169: 
>> caught SIGTERM, shutting down 
>> 
>> [Tue Jan 23 06:57:38.498538 2018] [mpm_prefork:notice] [pid 7753] AH00163: 
>> Apache/2.4.18 (Unix) mod_wsgi/4.5.5 Python/2.7.10 configured -- resuming 
>> normal operations 
>> 
>> [Tue Jan 23 06:57:38.498826 2018] [core:notice] [pid 7753] AH00094: Command 
>> line: 'httpd (mod_wsgi-express) -f 
>> /tmp/mod_wsgi-localhost:5000:501/httpd.conf -D FOREGROUND'
>> 
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