If You are not going to shuffle around Your tubes, then de-poisoning will 
not help prolong tube life as the heavily used numbers still wear out 
first. If You shuffle them they will have some mechanical stress every time 
that is done and maybe cause a leak. Having moveable tube mounts and switch 
their allocations in software when moved is one solution, but will it 
really be done over time? People are lazy by nature... 

The calendar tubes may benefit from de-poisoning as they shift a little bit 
too infrequent to keep their cathodes fresh. Just step thru the used 
cathodes at some hour when You are likely to be asleep. There are no need 
for fancy drivers, just let the cathodes float when not lit. The never used 
ones are just never used. No need to waste driver outputs on them. This is 
not a rocket science. 

In my opinion the best way to prolong tube life is to use lowest 
recommended current and use PWM to reduce brightness. In the well known 
Weston book he states that tube life is inverse proportional to I^2.5, that 
means a lot of wear for just a little bit more current. He also states that 
the mean current when pulsed (don't remember dutu cycle) just had an impact 
of I^1.5. He had no definite explanation for that, just empirical data from 
sputtering experiments.

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