> I would like to adapt the design found here 
> <http://www.desmith.net/NMdS/Electronics/NixiePSU.html> for a variable 300V 
> max output, instead of around 180–220V:

Unfortunately, these flyback supplies can only boost a voltage so far in a 
single step, and getting 300V out isn't really going to work with that circuit 
topology.  The easiest modification is to run it with 30V in (with a separate 
supply for the MAX1771).  The second easiest modification is to add a voltage 
doubler on the output.

> 
> I understand that the output voltage is adjusted by the resistors R1 and R2, 
> per the MAX1771 datasheet 
> <https://datasheets.maximintegrated.com/en/ds/MAX1771.pdf>:
> 
> 
> and that in this case a potentiometer is used to vary the voltage of R1. 
> However, I'm not sure how the above equations are used to arrive at the 
> voltage bounds specified in the schematic. Could someone explain? Using those 
> equations, what value of R2 should I substitute in for the one used in the 
> schematic to arrive at my desired maximum voltage of 300V?

With a little algebra, the equations from the data sheet become:

Vout = Vref(R2 + R1) / R1

In the circuit, the upper limit would be reached with VR1 at minimum, so the 
lower resistor would be 10k and the upper resistor would be 1.5M, so Vout = 
226.5V.  The lower limit would be with VR1 at maximum, which would make the 
lower resistor 15k, making Vout = 151.5V.

Making R2 higher might lead to noise problems, so raising the output voltage is 
probably better done by reducing R1.  Reducing R1 to 7.5k would give a maximum 
voltage of 301.5V, but again if you did that with the existing circuit, it 
would need to run on a higher input voltage (if you tried to get 300V out from 
12V in, you'd probably end up just burning some parts).

The note in the schematic is true: board layout is critical, not just for high 
efficiency, but to get it to work at all.  For beginning builders, I recommend 
the more robust 555 based circuit, even though it's less elegant and efficient, 
it's more tolerant to layout issues.  The fancier MAX1771 and MC34063 circuits 
are much less forgiving.

- John

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