You can use map for this...

 - http://nginx.org/en/docs/http/ngx_http_map_module.html#map

map $upstream_http_x_secured_page $nocache {
    "search string"             "1"
    default                     "";
}

location /foo {
    ...
    proxy_no_cache $nocache;
}

Posted at Nginx Forum: 
https://forum.nginx.org/read.php?2,278558,278563#msg-278563

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