I am not sure if this reference is helpful Faltaos DW, Urien S, Carreau V, Chauvenet M, Hulot JS, Giral P, Bruckert E, Lechat P. Use of an indirect effect model to describe the LDL cholesterol-lowering effect by statins in hypercholesterolaemic patients. Fundam Clin Pharmacol. 2006 Jun;20(3):321-30.
Ganesh --------------------------------------- Ganesh M Mugundu Graduate Student College of Pharmacy University of Cincinnati Cell: 513 417 4847 BLOG: http://pk-pd.blogspot.com/ WebPage: www.geocities.com/ganaish If you want to get somewhere, you have to know where you want to go and how to get there. Then NEVER, NEVER, NEVER GIVE UP." Norman Vincent Peale
