*The Washington DC Advanced PKPD course is filling up fast. If you want to be there and you haven't signed up already then please reply soon to this announcement!*

*_THE SHEINER ROWLAND ADVANCED COURSE IN _*

*_PHARMACOKINETICS & PHARMACODYNAMICS_*

*_ _*

*Dates: Sunday -- Friday May 3 - May 8, 2009*

* *

*               The Center for Drug Development Science*

*UCDC Campus
1608 Rhode Island Ave. NW*

*Washington**, DC USA** *





*A Workshop, presenting advanced aspects and applications of pharmacokinetics, pharmacodynamics and kinetic/dynamic data analysis in the medical and pharmaceutical sciences. *

* *

*_For whom intended:_**_ _**
The Workshop is designed for those who have a good working knowledge of basic concepts in pharmacokinetics, pharmacodynamics and data analysis and who now wish to extend their knowledge further. Emphasis will be placed on relating pharmacokinetics to underlying physiological processes and to pharmacodynamics, and on the analysis and modelling of pharmacokinetic and pharmacodynamic data. *

* *

*_Workshop content:_**
The mornings will be devoted to lectures; the afternoons to small-group workshops led by experienced tutors, in which participants will solve practical problems and develop facility with the techniques and approaches discussed in the lectures. The participants are encouraged to raise questions from their experience for discussion: time is specifically reserved for such informal discussions. *

*A course manual, comprising lecture outlines, derivations, problem sets with answers, and additional reading material will be provided. Participants should come with a scientific hand calculator. *

* *

*_Topics to be covered include:_*

* *

   * *Empirical models for pharmacokinetics and pharmacodynamics*
   * *Mechanistic models for pharmacokinetics (compartmental,
     physiological) and pharmacodynamics (receptor-theory) and combined
     PKPD (immediate and delayed effects) *
   * *Data analysis techniques for empirical or mechanistic modelling:
     point estimates, confidence intervals, hypothesis tests. *
   * *Population pharmacokinetics and pharmacodynamics*
   * *Disease progress and drug action modelling*
   * *Optimal design*

* *

*Faculty:*



*Leon Aarons *is a Professor and Director of Undergraduate Studies in the School of Pharmacy and Pharmaceutical Sciences, University of Manchester, UK. His research interest is in population and physiologically-based pharmacokinetics. He is co-editor of the Journal of Pharmacokinetics and Pharmacodynamics and executive editor of the British Journal of Clinical Pharmacology.

*Nick Holford* is Associate Professor of Clinical Pharmacology at the University of Auckland, Auckland, New Zealand. He has been involved in PKPD modelling for over 30 years. He has a particular interest in describing disease progression and the influence of drug treatments on disease.

*Mats Karlsson* is Professor of Pharmacometrics at the Faculty of Pharmacy, Uppsala University, Sweden. Since 1994, his research group has focused on methodological aspects of nonlinear mixed effects model building and applied PKPD modelling.

*France Mentré* is Professor of Biostatistics at the University Paris Diderot (Paris 7), France. She heads an INSERM research team on Methods and Models for therapeutic assessment in chronic diseases. She has worked on development and application of methods for nonlinear mixed-effects models in pharmacokinetics and pharmacodynamics for more than 20 years

*Stephen Duffull *is Professor of Clinical Pharmacy at the University of Otago, Dunedin, New Zealand. He runs a modelling and simulation lab within the School of Pharmacy. Research interests include optimal design, MCMC methods particularly in clinical toxicology and the influence of obesity on PKPD. He has been involved in the area of PKPD and nonlinear mixed effects modelling for more than 10 years.



*COURSE FEE: *

$3600 including breakfast, lunch, coffee breaks, reception, and one evening dinner.



       TO REGISTER FOR Advanced PKPD Course
       Washington, DC  May 3 -- May 8, 2009

Please click

https://www.123signup.com/event?id=zjdvr

to register online. Enrollment is limited to 50, so prospective participants are encouraged to register well in advance. Ability to understand and converse in English is essential.

A limited number of spaces at a reduced fee are available to academic/regulatory persons. Further details are available upon request to Julie Nelson: julie.nel...@ucsf.edu <mailto:julie.nel...@ucsf.edu>.

*COURSE LOCATION:*

The Center for Drug Development Science
UCDC Campus
1608 Rhode Island Ave. NW
Washington, DC *Map* <http://maps.yahoo.com/py/maps.py?BFCat=&Pyt=Tmap&newFL=Use+Address+Below&addr=UCDC+Campus+&csz=Washington+DC+20036&Country=20036&Get%A0Map=Get+Map>



*HOTEL ACCOMODATION: *

*Hotel rooms at a special rate are available at these hotels which are close to CDDS at the UCDC campus. *

* *

*The Beacon Hotel* - *Scott Circle*
1615 Rhode Island Ave. NW
Washington, DC  20036

(202) 296-2100* or  **(*800) 821-4367**

http://www.capitalhotelswdc.com/BeaconHotelWDC_com/directions.htm

*The Doubletree Hotel -- Scott Circle*
1515 Rhode Island Ave NW
Washington, DC 20036**

*(*202) 232-7000

http://doubletree1.hilton.com/en_US/dt/hotel/WASDTDT-Doubletree-Hotel-Washington-DC-District-of-Columbia/index.do

--
Nick Holford, Dept Pharmacology & Clinical Pharmacology
University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand
n.holf...@auckland.ac.nz tel:+64(9)923-6730 fax:+64(9)373-7090
http://www.fmhs.auckland.ac.nz/sms/pharmacology/holford

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