Andreas, PsN has functionality for automatically applying the CONT-data-item approach mentioned by Mark and Nick.
To run your model in nonmem with more than 20 input variables, you would simply type: execute --wrap_data run1.mod In a subdirectory PsN will create a new dataset and model file with CONT and other necessary components and run this in NONMEM. The nonmem output file, table files etc. will be returned to the directory where user runs execute. There are situations where the PsN-wrap_data functionality fails, but for these (rare) situations it also seems impossible to make the CONT-functionality to work "manually" (outside of PsN). It is not clear to me if these problems arise due to errors in the NONMEM documentation or implementation of the CONT data item, but again; it most often works! Cheers Jakob -----Original Message----- From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On Behalf Of Nick Holford Sent: 16 March 2009 14:48 To: nmusers Subject: Re: [NMusers] 20 variable limit in $INPUT Look in your NONMEM html\cont.htm. The CONT data item lets you specify additional input records which can be continued to allow more than 20 data items. Here is a description in more detail. http://www.cognigencorp.com/nonmem/nm/99aug272005.html I found this by searching with Google for "NONMEM cont data item". Much better than trying to use the NONMEM archive search which responded with: No matches were found for 'cont and data and (item or items)' andreas.kra...@actelion.com wrote: > > I am looking for a solution to get around the limit of 20 input > variables in nonmem. > The message you get with more than 20 variables in $INPUT is this: > > 16 $INPUT: NO. OF DATA ITEMS EXCEEDS 20. > STOP 4 statement executed > > I did not find anything in the archives or on the Web. I recall having > successfully done that in nonmem V, and I think it was about changing > the value of 20 to another value in a few files. > My original naive idea was that this was just a single change to the > SIZES file in nm VI but that seems to not be the case. > > To keep the discussion focused, I am not looking for workarounds like > solutions with concatenated values and an indicator variable. > For a change I am trying to get the software to adapt to the user's > needs instead of the usual opposite situation. > > Thanks for any pointers. > > Andreas > > ----- > > Andreas Krause, PhD > Lead Scientist Modeling and Simulation > > Actelion Pharmaceuticals Ltd > Gewerbestrasse 16 > CH-4123 Allschwil > Switzerland > The information of this email and in any file transmitted with it is strictly confidential and may be legally privileged. > It is intended solely for the addressee. If you are not the intended recipient, any copying, distribution or any other use of this email is prohibited and may be unlawful. In such case, you should please notify the sender immediately and destroy this email. > The content of this email is not legally binding unless confirmed by letter. > Any views expressed in this message are those of the individual sender, except where the message states otherwise and the sender is authorised to state them to be the views of the sender's company. For further information about Actelion please see our website at http://www.actelion.com > -- Nick Holford, Dept Pharmacology & Clinical Pharmacology University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand n.holf...@auckland.ac.nz tel:+64(9)923-6730 fax:+64(9)373-7090 http://www.fmhs.auckland.ac.nz/sms/pharmacology/holford