Dear Nmuser: I would like to do a data simulation .The distributions of the drug population pharmaockinetics were assumed to be normal.But the profile that I have got is Tmax, Cmax,and AUC(the means and variances are already known),instead of Ka,CL,and V. What the $PK modification should I have to do in the model where the advan2 has been taken in the $subroutine.
F=1.
Any suggestion would be appreciated.
Yours,ye hong bo
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