Dear NMUsers

We are investigating the purchase of a hyperthreaded dual quad-core machine (8 
physical cores; hyperthreaded to create 16 logical cores) with a view to 
reducing the time taken for those aspects of model validation that require 
multiple iterations e.g. bootstrapping, likelihood profiling.  Our current 
system uses NONMEM 7, with Intel Fortran running under Windows XP Professional, 
32 bit machine .  A licensed version of PLT Tools is used for graphical output 
and to facilitate model development and validation.

We are wondering whether a 64bit operating system would be preferred for 
optimal performance e.g.  64bit Windows 7?  Any comments or recommendations 
gratefully received.

With thanks and best wishes

Ann
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Ann Rigby-Jones PhD MRSC
Research Fellow in Pharmacokinetics & Pharmacodynamics
Peninsula College of Medicine & Dentistry

N31, ITTC Phase 1
Tamar Science Park
1 Davy Road
Derriford
Plymouth
PL6 8BX

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