Dear Nmusers: The PK/PD scientists here at ICON express our sincere condolences on the passing of Tom Ludden. As mentioned by several already, Tom was very instrumental in transitioning the NONMEM software development from the labs of Beal, Sheiner, and Boeckmann at UCSF, to Globomax, then to ICON. The development team at ICON was greatly aided in adding additional features from NONMEM VI to NONMEM 7 with his expert direction and his connections with many in the PK/PD modeling and population analysis community offering their inputs regarding desired features (and fixing a few bugs!). Tom continued with ICON all the way through the development of NONMEM 7.2 before his retirement in Spring 2011, and oversaw the incorporation of dynamic memory allocation, as well as parallel computing that were first incorporated in that version, which was a significant milestone in the performance of NONMEM. In a retirement speech some years ago Tom expressed that his greatest desire was that he was useful to the PK/PD and pharmacometrics field. He certainly accomplished this in a way few of us can ever hope to achieve.
Robert J. Bauer, Ph.D. Senior Director Pharmacometrics R&D ICON Early Phase 731 Arbor way, suite 100 Blue Bell, PA 19422 Office: (215) 616-6428 Mobile: (925) 286-0769 robert.ba...@iconplc.com<mailto:robert.ba...@iconplc.com> www.iconplc.com<http://www.iconplc.com/> <br /><br /> ICON plc made the following annotations. ------------------------------------------------------------------------------ This e-mail transmission may contain confidential or legally privileged information that is intended only for the individual or entity named in the e-mail address. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution, or reliance upon the contents of this e-mail is strictly prohibited. If you have received this e-mail transmission in error, please reply to the sender, so that ICON plc can arrange for proper delivery, and then please delete the message. Thank You, ICON plc South County Business Park Leopardstown Dublin 18 Ireland Registered number: 145835
