Dear All,

I am deeply saddened to hear this news. During my PhD in Minnesota, I had
the privilege of engaging with Dr. Ludden through Skype interactions. In
the advanced PK course taught by Dr. Bill Elmquist, we had a unique
assignment to write an essay on the scientific impact and life journey of a
notable scientist in the field of Pharmacometrics. I don't recall how I
chose Dr. Ludden, but he was incredibly welcoming and generously shared
numerous stories about his personal and professional experiences. I cherish
those conversations and the insights he provided. I hope to find this essay
in one of my emails, and if I do, I will share it with you

Rest in peace, Dr. Ludden.

Warm regards,

Vijay

On Mon, Aug 5, 2024 at 4:49 PM Rene Bruno <rbruno...@gmail.com> wrote:

> Dear all,
>
> This is indeed very sad. I concur with everyone. Ton was a very nice
> person, always open to listen to you and provide advice and support. II met
> with him a couple of times in the early 90ies and particularly in one
> formal meeting (probably in 1992) when he was heading Pharmacometry at FDA.
> He has been so supportive to my popPK/PD plans to support the filing of
> docetaxel (Taxotere) that when I got back in my company (Rhone Poulenc, now
> Sanofi) that the SVP of Regulatory asked me "what it is that you are doing?
> population PK???? Given such positive feedback from Tom (and FDA) I got
> full support to get the data and analysis done on time for the filing.
> Tom's support changed my life as well as the one of patients
> receiving Taxotere with the Boxed Warning about elevated hepatic enzymes
> (still in the US PI) and the dose adjustment in the EU SCP.
>
> I will be indebted to him forever.
>
> René
>
>
> <https://www.avast.com/sig-email?utm_medium=email&utm_source=link&utm_campaign=sig-email&utm_content=webmail>
>  Sans
> virus.www.avast.com
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> <#m_-7736047338385682954_DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2>
>
> Le ven. 2 août 2024 à 20:56, Riley, Steve <steve.ri...@pfizer.com> a
> écrit :
>
>> Dear NM-Users,
>>
>>
>>
>> Regrettably, I am writing to let you know that Dr. Ludden passed away
>> Tuesday evening, 30JUL2024.
>>
>> I was able to get there over the weekend prior to visit him and his
>> family.
>>
>> During his wakeful moments we had some good scientific discussions.
>>
>> We talked a lot about NONMEM and how its functionality and utility has
>> expanded since he retired. He was pleased to hear about the changes.
>>
>> He was surrounded by family for the days leading up to the end. They were
>> all appreciative that I was able to get there and tell him (and them) how
>> much he meant to all of us and the impact he had on our careers.
>>
>>
>>
>> I think memories of Dr. Ludden were characterized perfectly by Marc
>> Gastonguay, “I am forever grateful for the positive impact that Tom had on
>> my life and career, not to mention the tremendous, although often
>> underappreciated, contributions he made to the disciplines of clinical
>> pharmacology and pharmacometrics. His humble brilliance will be missed and
>> fondly remembered.”
>>
>>
>> Steve Riley
>>
>>
>>
>

-- 
~Vijay

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