Hi Douglas,
On top of this, it might be the encryption only started with version 7.
I remember looking at the FOCE code myself, the earliest version I
installed was 5 so that one was open. I believe 6 was open as well,
perhaps someone can confirm that.
Good luck with your paper!
Jeroen
http://pd-value.com
jer...@pd-value.com
@PD_value
+31 6 23118438
-- More value out of your data!
On 04-12-2024 15:41, Bonate, Peter wrote:
Personally I don’t think it was the use of FOCEI that led to NONMEM
taking off, it was that you could run it on personal computers, which
were just starting to be powerful enough to handle to computational
load. This was back when computers had numbers for names, like 386
and 486. I think this started with NONMEM IV.
There was a history of NONMEM webpage that Icon maintained, but when I
checked today, it no longer looks like it is functional.
https://nonmem.iconplc.com/nonmem_history/NONMEM_history4.pdf
Pete Bonate
*Peter Bonate, PhD*
Suzerain, New Technologies
Early Development
Astellas
2375 Waterview Drive
Northbrook, IL 60062
peter.bon...@astellas.com <mailto:peter.bon...@astellas.com>
(224) 619-4901
*From:*owner-nmus...@globomaxnm.com <owner-nmus...@globomaxnm.com> *On
Behalf Of *Eleveld, DJ
*Sent:* Wednesday, December 4, 2024 5:39 AM
*To:* nmusers <nmusers@globomaxnm.com>
*Subject:* [NMusers] Historical question
Hi All, I am writing a paper on some C language code I have written
that does FOCE. I want to write a few sentences about the history of
NONMEM but I’m not 100% sure it is correct. Can someone knowledgeable
give me some feedback on this?
Hi All,
I am writing a paper on some C language code I have written that does
FOCE.
I want to write a few sentences about the history of NONMEM but I’m
not 100% sure it is correct.
Can someone knowledgeable give me some feedback on this?
“NONMEM software was developed at USCF in the late 1970s and became
the de-facto industry standard when the first-order-conditional
estimation with interaction (FOCE-I) method reaching wide use in the
field. NONMEM was open source until version 5 when the rights were
obtained by Icon PLC and it became encrypted-source. The investment of
Icon PLC has resulted in considerable NONMEM development with many
bug-fixes and new features available in current version 7.5.1. ”
Warm regards,
Douglas Eleveld
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