Korag and Sam, As you may know, we have recently initiated a new SIG at HL7 called Clinical-Genomics, focusing on the use of genomic data in clinical scenarios. In particular I've been working on the usecase of tissue typing where more and more genomic data are being used to make the new methods of bone marrow transplantation more successful. In that SIG we have other people working on usecases in the areas of genomic-based diagnostics and clinical trials. in the later, patients are being tested for their genetic profile and conclusions are made accordingly so that inappropriately prescription could be avoided.
In all these usecases we are trying to find the commonalities in the data representations (e.g., the representation of allele and its SNPs) and then come up with a domain information model using the HL7 tooling. I agree with you that genomic data are not just different data types and they do need special attention.... :-) I would be very happy to share this work or even collaborate with OpenEHR members of are interested in this domain and use the OpenEHR tools. At IBM Research we have been working intensively with a research center in Canada (iCapture) where mass clinical and genomic data were correlated to explore lung and hurt diseases (see InfoWorld article at http://www.infoworld.com/article/03/03/26/HNicapture_1.html). Thanks, Amnon. ------------------------------------------ Amnon Shabo (Shvo), Ph.D. Life Sciences Solutions IBM Research Lab in Haifa "Sam Heard" <sam.heard at bigpond.com>@openehr.org on 17/05/2003 01:10:52 Please respond to "Sam Heard" <sam.heard at bigpond.com> Sent by: owner-openehr-technical at openehr.org To: "Koray Atalag" <atalagk at hacettepe.edu.tr>, <openehr-technical at openehr.org> cc: Subject: RE: Genetic information and RM (data types and structures) Korag This may well be the way to go soon - but I would think that an external datatype would be better for the moment as the representation will probably not be uniform (and openEHR should not impose uniformity in such a domain). Also, we would see the genome as only forming part of the genetic record - as there will need to be a lot of other information present to make healthcare work. What do you think? Cheers, Sam Heard ____________________________________________ Dr Sam Heard Ocean Informatics, openEHR Co-Chair, EHR-SIG, HL7 Chair EHR IT-14-2, Standards Australia Hon. Senior Research Fellow, UCL, London 105 Rapid Creek Rd Rapid Creek NT 0810 Ph: +61 417 838 808 sam.heard at bigpond.com www.openEHR.org www.HL7.org __________________________________________ > -----Original Message----- > From: owner-openehr-technical at openehr.org > [mailto:owner-openehr-technical at openehr.org]On Behalf Of Koray Atalag > Sent: Thursday, 15 May 2003 11:10 PM > To: openehr-technical at openehr.org > Subject: Genetic information and RM (data types and structures) > > > Hi, > > I had problems wth my membership with the list for a while so I could not > catch up with recent stuff but during this time I had some time to examine > openEHR documents posted on the website. As a person who had > previously been > involved with bioinformatics and especially human genomic databases, some > part in my mind still reminds me of the fact that one day all these > information shall be integrated. Also personally, I believe the approach > taken in openEHR shall form the baseline for future of EHR systems. So I > would like this issue to be considered during these discussions. Enough of > good wishes, here is my question: > > Is there a specific way to represent genomic data of a patient (Either > Nucleic Acid sequences or protein sequences) in the Reference Models or is > the general purpose text data type is thought to be the solution? > I think it > could be wise to create a new class with its own attributes, methods and > constraints right into the RM because with this speed of biologic > evolution > I don't think the genetic code and concepts are going to change > for a couple > million years! > > Best regards, > > Koray Atalag > > > > - > If you have any questions about using this list, > please send a message to d.lloyd at openehr.org > - If you have any questions about using this list, please send a message to d.lloyd at openehr.org - If you have any questions about using this list, please send a message to d.lloyd at openehr.org
