On Tue, Feb 01, 2005 at 08:00:39AM +0930, Sam Heard wrote:
> 
> Age is time after birth - we are not going to change that.
>

That's fine ... now for the second ...

> We have agreed that we need to record one more date in the demographic 
> model - which is 'approximate date of conception', or 'expected date of 
> birth'

We should  confine ourselves with available  recommendations of
the WHO, which  is based on LMP only. All  other parameters are
derived from this. Besides, LMP is a fixed recordable event.

>From the  XML, I understand,  you may  be thinking in  terms of
some gestational history  for the newborn. Calculations  can be
done from  the mother's  obstretic history,  as per  parameters
defined by the WHO. This is the current recommendations:

o LMP = first day of the Last Menstrual Period
o Prematurity      = birth < (LMP + 37 wk) gestation
o Normal gestation = birth > (LMP + 38 wk) < (LMP + 41 wk)
o Postmaturity     = birth > (LMP + 42 wk) gestation

Please note the hazy zones between 37-38th week and 41-42nd wk.
We can expand the band of normalcy from 37 to 42, and eliminate
this vagueness without significant real-life issues.

Date of Conception is normally not used because it depends upon
the periodicity of the menstural cycle of the mother and  other
factors. The variations are too many to be correctly instituted
as a measure.

If you are thinking of an additional  DV_Textual_ordered  class
as seen from the XML (quoted below) then:

> <DV_Textural_ordered>
>       <text>"Birth"</text>
>       <value type="DV_QUANTITY">
>               <magnitude>0<magnitude>
>               <units>"days"</units>
>       </value>
> </DV_Textural_ordered>
>

o The 'magnitude' would obviously have to be taken from the EDD
  (Expected Date of Delivery). Since the  'normal range' itself
  is a wide band, with the midian point at (LMP + 274 days) the  
  above representation would have to be re-structured.

o Incidentally, there is also an alternate 'prematurity' defini-
  tion based on weight - the original WHO recommendation of 1948
  (viz birth weight < 2500 gm). This covers the "small-for-date"
  newborns, burn within normal gestation period. This  is  still
  in use in several countries (mainly developing countries).This
  should not be ignored.

o Postmaturity is another factor which would  need  inclusion in
  such a textual class. To keep it simple and  self explanatory,
  I suppose, the following should do:

  <DV_Textural_ordered>
      <text>"Gestation_period"</text>
      <value type="DV_QUANTITY">
          <magnitude>0<magnitude>
          <units>"weeks"</units>
      </value>
  </DV_Textural_ordered>

  <DV_Textural_ordered>
      <text>"Birth_weight"</text>
      <value type="DV_QUANTITY">
          <magnitude>0<magnitude>
          <units>"grams"</units>
      </value>
  </DV_Textural_ordered>

Keeping the gestational period kept as an absolute number leaves
things like  normal range,  prematurity,  postmaturity etc  as a
search/ derived parameter. Any changes in WHO criteria would not
affect the database.

Just a suggestion ...

Dr USM Bish
Bangalore

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