Tom,
Does leaving "the current DV_QUANTITY the way it is" include the ability to
record "< 5 mmol/L" for example?

Heath 
 

-----Original Message-----
From: [email protected]
[mailto:owner-openehr-technical at openehr.org] On Behalf Of Thomas Beale
Sent: Monday, 20 March 2006 5:30 AM
To: openehr-technical at openehr.org
Subject: Re: Pathology numeric values not supported in DV_Quantity

Grahame Grieve wrote:
> I agree with this - that's it good enough now.
>
> I think this thread is starting to talk about things which aren't 
> properly part of the data type, they are conceptual things about the 
> result values, and should be modelled explicitly in the archetypes.
Grahame,

is it your feeling that we need to have a better model of accuracy, i.e. 
more like the confidence interval idea? Or are we ok with what we have? 
My gut feeling is to leave the current DV_QUANTITY the way it is and
consider either
a) doing nothing - treat Tim's requirements as requirements not on primary
data going into the EHR, but on generated data of the kind found in an
epidemiological/statistical style of system or
b) add a variant of DV_QUANTITY (probably a subtype) that does the full deal
(and is convertible into a vanilla DV_QUANTITY).

thoughts anyone?

- thomas

>
> Grahame
>
>
>
>
> Thomas Beale wrote:
>>
>> Sam would be better able to give an idea of all the health 
>> professionals who have been consulted, but certainly in Australia, 
>> Vince McCauley (a pathologist) has been extremely helpful on 
>> pathology result detail. Also, people like Heath Frankel and Grahame 
>> Grieve who have worked with HL7v2 messages for years have provided 
>> quite a lot of input on details (for example in Release 1.0, there is 
>> now a summary attribute for Historical data structures, directly due 
>> to Grahame's advice on the shape of lab data his software handles - 
>> see 
>>
http://www.openehr.org/uml/Browsable/_9_0_76d0249_1109157527311_729550_7234R
eport.html).
>>
>>
>> Is it enough? At this stage I would be fairly confident that the 
>> models are good enough for most pathology data (certainly everything 
>> any of the docs working with openEHR has seen). Are they perfect? Of 
>> course not. We always need more input. The confidence level stuff 
>> implied by your requirements (let's treat them as epi/public health 
>> data requirements) would make things better; we just have to 
>> determine a) what scope of data they apply to (e.g. how much 
>> sophistication do we need in the EHR compared to say a dedicated data 
>> warehouse designed for statistical studies?) and b) how to add them 
>> to the current model in a way compatible with what is there.
>>
>> I think that he idea of a workshop is a good one; I would prefer to 
>> see clinical professionals here take up the suggestion and do 
>> something with it; I don't see these kinds of discussions as being IT 
>> driven - they are all about articulating requirements.
>>
>> - t
>>
>>
>> Tim Churches wrote:
>>> Thomas Beale wrote:
>>>  
>>>> Tim Churches wrote:
>>>>   
>>>>>  
>>>>>     
>>>>>> Tim, if the accuracy_is_percent attribute was upgraded to a coded 
>>>>>> value, could you suggest a set of meanings that would cover all 
>>>>>> the epi/PH needs?
>>>>>>             
>>>>> You'll have to tell me what that would involve. A single coded value?
>>>>> Upper and lower limits? Confidence level. Type of limit?
>>>>>         
>>>> well, essentially what you are proposing     
>>>
>>> Not proposing anything, I'm just asking the question "Have you 
>>> thought about this?"
>>>
>>>  
>>>> would require (let's not get
>>>> too pure about how I use the word "accuracy" here for the moment):
>>>> - lower accuracy limit: Real
>>>> - upper accuracy limit: Real
>>>> - accuracy limit type: coded term
>>>> - confidence level (or this could be part of the previous coded 
>>>> attribute, since only a small number of confidence bands are used 
>>>> in practice aren't they?)
>>>>
>>>> Now, what we currently have is a set of general purpose quantity 
>>>> classes designed to enabled recording of any quantitative data we 
>>>> have come across so far. Between various MDs such as Sam, Vince and 
>>>> others, I think we have pathology covered from a practical point of 
>>>> view (well, we do once we get this <, >, etc thing sorted).
>>>>     
>>>
>>> Just curious: have you had much input from pathologists, 
>>> microbiologists and lab scientists? The more one talks to such 
>>> people, the more one discovers about the uncertainties inherent in 
>>> certain assay techniques, and the differences in the scalar (and 
>>> qualitative or Boolean) results produced by different assay kits and 
>>> different labs.
>>>
>>> Oh, there's another form of uncertainty which typically is of 
>>> relevance to Boolean/dichotomous results (positive/negative, 
>>> detected/not detected
>>> etc) and that is the sensitivity and specificity of the test, or the 
>>> related quantities PPV (positive predictive value) and NPV. (Note to 
>>> computer scientists: "specificity" and "sensitivity" are cognate 
>>> with "precision" and "recall".)
>>>
>>>  
>>>> The real question is: what is the type & origin of data that need 
>>>> to represented in the more sophisticated way that we are now 
>>>> suggesting? Is it a different category of data? Should be leave the 
>>>> current DV_QUANTITY as is and add a new subtype? Or is it that we 
>>>> should consider a quantity with a 95% T-distribution confidence 
>>>> interval as a pretty normal thing?
>>>> Should we then start considering the "simple" idea of a symmetric 
>>>> accuracy range (+/- xxx) as really just one specific type of  a 
>>>> confidence interval (it might translate to something like 98% on a 
>>>> normal curve). In other words, should we generalise he "accuracy"
>>>> notion
>>>> into a "confidence interval" notion?
>>>>     
>>>
>>> I think that a one or two day workshop with a range of pathologists, 
>>> microbiologists, lab scientists, epidemiologists and statisticians 
>>> (and some clinicians and computer scientists, of course) would 
>>> suffice to come up with sensible answer to your question. I'd be 
>>> happy to participate and to suggest other participants. First half 
>>> day would need to be spent bringing everyone up to speed on openEHR 
>>> so they understand the nature of the question(s) to be addressed 
>>> (and a good means of spreading the openEHR gospel while you're at 
>>> it...).
>>>
>>> Might be possible to hold a cyber-workshop instead, via email or 
>>> real-time conferencing. The former would be much slower, of course.
>>>
>>> Tim C
>>>
>>>
>>>
>>>   
>>
>>
>


--
____________________________________________________________________________
_______
CTO Ocean Informatics (http://www.OceanInformatics.biz) Research Fellow,
University College London (http://www.chime.ucl.ac.uk) Chair Architectural
Review Board, openEHR (http://www.openEHR.org)



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