Considering how prevalent Photoshop is in current photographic workflow, perhaps this isn't very much off topic at all. Tonight, while exploring the program, I discovered a new (to me) tool, buried beneath the Blur tool along with the Smudge tool. It's the Sharpen tool.
You can use it as another method to selectively sharpen without sharpening the whole picture ... Use the Sharpen Tool set at, for example, 50% strength with a soft edged brush to selectively sharpen eyes or other specific points of interest. Set the brush size accordingly & click those areas until you get the desired sharpness. What's nice about the tool is that it's very adjustable; it can be used in Normal, Darken, and Lighten modes and it can also be faded, like many other tools, including, as I just discovered, Unsharp Mask. Try it out ... you may like it and find some uses for it. Shel