>...  The fact that some individuals don't have legs
> , i.e. not bipedal,  doesn't make them non-humans for moral or legal
> purposes.

having two legs is what makes us human? remember, we also lack feathers.

> The fact that some individuals don't have functioning gonads etc.
> doesn't become a basis for discarding the biological definition of sex
> or render it an invalid biological concept.

there's nothing wrong with a biological conception of sex. But
defining sex totally in terms of reproduction seems off.

-- 
Jim Devine / "Segui il tuo corso, e lascia dir le genti." (Go your own
way and let people talk.) -- Karl, paraphrasing Dante.
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