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weight gain cause by prolactinoma?

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From: PedsProf

Weight gain, definitely -- I second that.  And, like Cora Lynn, I'm compact (5'2 3/4" -- and I take great pride in that last 3/4"!!), so it doesn't take much to really change how I look and feel.
 
It took six years of symptoms for me to finally be diagnosed, and that was seven years ago.  I just learned about the weight gain -- both in literature and through personal experience -- within the last two months.
 
During seven years of bromocriptine (and horrible side effects), I also went through a divorce and finished a doctoral degree -- so I attributed weight loss to a rather prolonged period of stress. 
 
Got my wake-up call in the past two months.  Stopped bromocriptine because the side effects -- to me -- were worse than the symptoms of high prolactin itself.  As far as I remembered. 
 
I was off meds for 7 weeks, and although weight gain was not immediately noticeable, it picked up swiftly as PRL levels climbed.  I gained 10 lbs in about five weeks, and had PRL tested at the end of those 5 weeks prior to regular Endo. appointment (it was 120).  Quickly made the connection between increase in PRL and increase in backside!!!  I had been eating incredibly well and exercising more -- yet growing. 
 
This was confirmed when I restarted treatment with new meds -- Dostinex.  Within the first week, 5 lbs melted off -- this was largely excess fluid.  Belly pooch -- which is not normal for me (don't hate me -- I have other curses, trust me :-) ) -- disappeared. 
 
 I am hoping that the rest will follow as I build tolerance to new meds and begin to increase dose. Also hoping that Dostinex will finall lower PRL to target levels.  Even on 10 mg/day of bromocriptine, lowest PRL was mid 40's.  In side-by-side blinded comparison trials, Dostinex was more effective (fingers crossed!!).  I'm scheduled for monthly bloodwork to check PRL, so I will be able to correlate levels with body weight. 
 
 

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