Hi Diane, Have you had your vitamin levels checked? Vitamin deficiencies can cause muscle, bone, and joint pain. I have low vitamin D and I have a lot of pain. That is just one possible cause for your pain...I know that there are many. I blamed my pain on the hormonal imbalance the last three years-now I know I have low vitamin D (caused by the hormonal imbalance) that causes my pain. Hopefully, the supplements will kick in, soon. GH deficiency can also cause muscle and joint pain. You will probably feel better on GH replacement. You will also have more energy and less fatigue on GH. Why haven't they prescribed GH replacement? Take care. You're in my prayers. Meri | 