If you have GH deficiency and are being tested for Cushings, your physician will not put you on GH therapy. Typically in Cushings, GH is low. There are some papers that suggest that GH supplementation in hypopit patients can actually lower cortisol levels. Similar studies have been done with patients who have had 1st surgeries with similar results. Your doctor doesn't want to muddy the testing by putting you on a drug that potentially could delay your diagnosis, should he truly suspect you have Cushings. From my point of view, I know a few Cushings patients who had co-sereting GH tumors (that didn't show biochemically), and these patients were very, very hard to diagnose with Cushings.The cocommittant secreting of GH was found during pathology. It is doubtful that your tumor "went away". Tumors that cause Cushings are often small, and up to 55% are never seen on MRI. Most MRI's have a 3mm slice. The pitutiary is a very small structure, and that "slice" could easily miss a small tumor. The dynamic MRI is used to show delays in contrast filling, that hopefully shows these small tumors, but there is no guarantee. When I did my MRI's they were always radiologically normal, but my neurosurgeon would point the tumor out on the films every time I went to see him (go figure). When I did my dynamic images, the tumor showed up on the left side, then a second set of images showed it on the right side. When the surgeon went in, he found the majority of the tumor at the right midline, with some extention into the left gland area. The job for your doctor is to do biochemical testing to prove Cushings (in the laboratory). Once your doctor proves the disease, then an Petrosal Sinus Sampling or a Cavernous Sinus Sampling is done to see of the source of the hypersecretion is at the pituitary or from an ectopic source (tumor somewhere else in the body). The test can be used to figure out what side of the gland the tumor is most likely on, but the surgeon will look during surgery, to ensure thetest lateralization was correct. Cushing is a terrible disease, and if the surgeon cannot find the tumor, he will most likely go by the results of the sinus sampling, and remove the side of the pituitary that the testing indicated the source was coming from. The odds for correctly predicting which side is about ~70% according to publications. - I can get you back up references if you need. Minnie | 