I guess any medication that lowers prolactin could be referred to chemotherapy. You need to clarify with the physician what the treatment really is. ![]() I looked for "new" chemotherapy formulations to treat hyperproalctinemia and could not find any. The assumption is that the 'chemotherapy' would be used to lower the prolactin levels. There are a few drugs that can be used to lower hyperprolactinemia - the most effective used drugs are those that are used to increase dopamine and most often are bromocriptine and dostinex. I would figure that the medication (chemotherapy) discussions to treat the hyperproalctinemia would originate from the endocrinologists office, but actually, I am pretty impressed that the neurosurgeon has taken an active role in getting your daughter help. ![]() Current medications used to treat hyperprolactinemia are: Cabergoline Bromocriptine Pergolide Quinagolide I understand his concern if she is not responsive to prolactin lowering drugs, and there is a very real concern about tumor growth. In that case, it seems to me that he would want to discuss ways to control tumor growth, as that is what neurosurgeons are typically concerned about. It would not surprise me therefore, if he suggested a radiosurgery therapy to control the tumor growth. This would not necessarily control the hyperprolactinemia, but it may be very affective at stopping tumor growth and avoiding yet a second surgery. You need to talk with your daughter's endo so you can understand the risk vs benefit of not trying to treat the hyperprolactinema. You also need to clarify the 'chemotherapy' treatment. What is it exactly? Some prolactinomas don't need medical management. That decision is individual and is based alot on tumor size, and other hormonal profiles. Hope this helps! Minnie | 